您好，欢迎访问北京市农林科学院 机构知识库！
北京市农林科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

N-Carbamylglutamate Improves Reproductive Performance and Alters Fecal Microbiota and Serum Metabolites of Primiparous Sows during Gestation after Fixed-Time Artificial Insemination

文献类型： 外文期刊

作者： Feng, Tao 1 ; Xiao, Linli 1 ; Bai, Jiahua 1 ; Ding, Hongxiang 1 ; Pang, Liyan 1 ; Song, Yuqing 1 ; Qin, Yusheng 1 ; Xu, Xiaoling 1 ; Wang, Jing 1 ; Liu, Yan 1 ;

作者机构： 1.Beijing Acad Agr & Forestry Sci BAAFS, Inst Anim Husb & Vet Med IAHVM, Beijing 100097, Peoples R China

2.Oklahoma State Univ, Joint Lab Anim Sci IAHVM BAAFS, Beijing 100097, Peoples R China

3.Oklahoma State Univ, Div Agr Sci & Nat Resource, Beijing 100097, Peoples R China

关键词： N-carbamylglutamate; fixed-time artificial insemination; sow reproductive performance; microbial community; metabolic profiles

期刊名称：BIOLOGY-BASEL （ 影响因子：5.168； ）

ISSN：

年卷期： 2022 年 11 卷 10 期

页码：

收录情况： SCI

摘要： Simple Summary Larger litter size (born alive) and higher uniformity of piglets' birth weight are the most desired characteristics in pig production. Application of N-carbamylglutamate (NCG) was shown to increase litter size and decrease the coefficient of variation of piglets' birth weight from sows after conventional artificial insemination. In this study, we report that, in sows after fixed-time artificial insemination (FTAI), NCG improved the number of piglets born alive and the coefficient of variation of birth weight through direct effects (increased serum NCG levels) and indirect effects (altered intestinal microbiome and serum metabolites). These findings indicate that NCG can improve reproductive performance by improving both the number of piglets born alive and the uniformity of piglets' birth weight in sows after FTAI. N-carbamylglutamate (NCG) supplementation during gestation improves reproductive performance in sows after conventional artificial insemination. However, whether NCG can improve reproductive performance and change fecal microbiota and serum metabolite levels during pregnancy in sows after fixed-time artificial insemination (FTAI) remains unclear. Two hundred multiparous sows were assigned a diet from mating until farrowing: control (corn-soybean meal) or NCG supplementation (0.05% NCG). At days 30, 70, and 110 of gestation and after farrowing, maternal microbial diversity and serum metabolites were studied. Supplementation of NCG increased the number of piglets born alive and the litter weight (all p < 0.05) and altered the fetal microbial community during gestation. Some genera were particularly abundant at different time points during gestation and after farrowing, but none were commonly abundant across all four time points. Metabolic analysis revealed that NCG supplementation significantly increased the serum concentrations of NCG, ferulic acid, cinnamoylglycine, 3-phenyllactic acid, and gamma-glutamylglutamic acid in the NCG group compared with levels in the control group. Our results reveal that NCG supplementation during gestation improves reproductive performance in sows after FTAI, exerting both direct (increased serum NCG levels) and indirect effects (altered intestinal microbiome and serum metabolites) on sow reproduction and, ultimately, improving placental and fetal development.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：北京市农林科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台