文献类型： 外文期刊
作者： Wang, Bo 1 ; Bai, Xiaolong 1 ; Zhang, Min 1 ; Liu, Xiangxiang 5 ; Dara, Muhammad Zulqar Nain 1 ; Liu, Lingjing 1 ; Ou, Mingming 1 ; Li, Dayong 1 ; Wang, Jiyang 2 ; Liu, Ling 1 ; Sun, Wenxian 1 ;
作者机构： 1.Jilin Agr Univ, Coll Plant Protect, Jilin Prov Key Lab Green Management Crop Pests & D, Changchun 130118, Peoples R China
2.China Agr Univ, Coll Plant Protect, Beijing 100193, Peoples R China
3.China Agr Univ, Key Lab Pest Monitoring & Green Management, Minist Agr, Beijing 100193, Peoples R China
4.Chinese Acad Trop Agr Sci, Environm & Plant Protect Inst, Haikou 571101, Peoples R China
5.Jilin Agr Univ, Coll Chinese Med Mat, Changchun 130118, Peoples R China
6.Yunnan Univ, Ctr Life Sci, Sch Life Sci,State Key Lab Conservat & Utilizat Bi, Yunnan Key Lab Cell Metab & Dis, Kunming 650091, Peoples R China
关键词： ustilaginoidin D; rice false smut; mice; hepatotoxicity; human health
期刊名称：TOXINS （ 影响因子：4.0； 五年影响因子：4.5 ）
ISSN：
年卷期： 2025 年 17 卷 5 期
页码：
收录情况： SCI
摘要：
Ustilaginoidin D is a type of bis-naphtho-gamma-pyrone mycotoxin produced by Ustilaginoidea virens, the causal agent of rice false smut. Although previous studies have demonstrated the inhibitory effect of ustilaginoidin D on ATP synthesis and cancer cell growth in mice, its specific health risks remain unclear. Here, we reveal that ustilaginoidin D is highly toxic to mice with an LD50 value of 213 mg /kg
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