Preparation and characterization of catechol-functionalized chitosan thermosensitive hydrogels
文献类型: 外文期刊
作者: Zhang, D. Y. 1 ; Hu, Z. 1 ; Lu, S. T. 1 ; Li, S. D. 1 ; Yang, Z. M. 2 ; Li, P. W. 2 ;
作者机构: 1.Guangdong Ocean Univ, Sch Chem & Environm Sci, Dept Appl Chem, Zhanjiang 524088, Guangdong, Peoples R China
2.Chinese Acad Trop Agr Sci, Agr Prod Proc Res Inst, Zhanjiang 524001, Guangdong, Peoples R China
期刊名称:2ND INTERNATIONAL CONFERENCE ON MATERIAL STRENGTH AND APPLIED MECHANICS
ISSN: 1757-8981
年卷期: 2019 年 629 卷
页码:
收录情况: SCI
摘要: Catechol functionalization of chitosan was modified by EDC coupling reaction and then catechol-functionalized chitosan thermosensitive hydrogels were prepared by catechol-functionalization of chitosan with beta-glycerophosphate disodium as a thermosensitizer. The hydrogels were then characterized by FTIR, H-1-NMR, SEM and rheology analysis. The results demonstrated that the thermosensitive hydrogels were prepared at 37 degrees C within several minutes by mixing 2% catechol-functionalized chitosan with 30% beta-glycerophosphate disodium at a ratio of 8:2, and these thermosensitive hydrogels with porous network structure were expected to be developed as biomedical materials with wide applications.
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