Chemical constituents from ethanol extract of Polyalthia rumphii branches and their cytotoxicity evaluation
文献类型： 外文期刊
作者： Wang, Tianshan 1 ; Wu, Xiaopeng 3 ; Liu, Yanping 1 ; Luo, Youping 1 ; Li, Xiang 1 ; Zhou, Yujie 1 ; Yang, AiPing 1 ; Yan, 1 ;
作者机构： 1.Hainan Normal Univ, Coll Chem & Chem Engn, Haikou, Hainan, Peoples R China
2.Hainan Normal Univ, Minist Educ, Key Lab Trop Med Plant Chem, Haikou, Hainan, Peoples R China
3.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou, Hainan, Peoples R China
关键词： Alkaloids; Lignan; Gossypol derivative; Cytotoxic activity; Polyalthia rumphii
期刊名称：REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY （ 影响因子：2.01； 五年影响因子：2.534 ）
ISSN： 0102-695X
年卷期： 2018 年 28 卷 2 期
页码：
收录情况： SCI
摘要： Twelve known compounds, including eight alkaloids, three lignans and one gossypol derivative, were isolated from the branches of Polyalthia rumphii (Blume ex Hensch.) Merr., Annonaceae. The chemical structures were determined by spectroscopic methods and comparison with literature data. All the isolates were evaluated the cytotoxicity against three human cancer cell lines: Hela, MCF-7 and A549, the results showed that partial of isolates displayed weak cytotoxicities with the IC50 values ranging from 25 to 40 mu g/ml. (C) 2018 Sociedade Brasileira de Farmacognosia. Published by Elsevier Editora Ltda.
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