文献类型： 外文期刊

作者： Li, Dawei ¹ ; Geng, Zedong ² ; Xia, Shixuan ¹ ; Feng, Hui ² ; Jiang, Xiuhan ¹ ; Du, Hui ¹ ; Wang, Pei ¹ ; Lian, Qun ¹ ; Zhu, Yanhui ¹ ; Jia, Yuxin ³ ; Zhou, Yao ¹ ; Wu, Yaoyao ⁴ ; Huang, Chenglong ² ; Zhu, Guangtao ³ ; Shang, Yi ³ ; Li, Huihui ⁵ ; Staedler, Thomas ⁷ ; Yang, Wanneng ² ; Huang, Sanwen ¹ ; Zhang, Chunzhi ¹ ;

作者机构： 1.Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen Branch, Minist Agr & Rural Affairs,Guangdong Lab Lingnan M, Shenzhen 518120, Peoples R China

2.Huazhong Agr Univ, Natl Ctr Plant Gene Res Wuhan, Natl Key Lab Crop Genet Improvement, Hubei Hongshan Lab, Wuhan 430070, Peoples R China

3.Yunnan Normal Univ, AGISCAAS YNNU Joint Acad Potato Sci, Yunnan Key Lab Potato Biol, Kunming 650000, Peoples R China

4.Nanjing Agr Univ, Coll Hort, Nanjing 210095, Peoples R China

5.Chinese Acad Agr Sci, Inst Crop Sci, 12 Zhongguancun South St, Beijing 100081, Peoples R China

6.Chinese Acad Agr Sci, Nanfan Res Inst, Sanya 572024, Peoples R China

7.Swiss Fed Inst Technol, Inst Integrat Biol, CH-8092 Zurich, Switzerland

8.Swiss Fed Inst Technol, Zurich Basel Plant Sci Ctr, CH-8092 Zurich, Switzerland

9.Chinese Acad Trop Agr Sci, Haikou 571101, Peoples R China

期刊名称：NATURE COMMUNICATIONS （ 影响因子：15.7； 五年影响因子：17.2 ）

ISSN：

年卷期： 2024 年 15 卷 1 期

页码：

收录情况： SCI

摘要： The genetic analysis of potato is hampered by the complexity of tetrasomic inheritance. An ongoing effort aims to transform the clonally propagated tetraploid potato into a seed-propagated diploid crop, which would make genetic analyses much easier owing to disomic inheritance. Here, we construct and report the large-scale genetic and heterotic characteristics of a diploid F2 potato population derived from the cross of two highly homozygous inbred lines. We investigate 20,382 traits generated from multi-omics dataset and identify 25,770 quantitative trait loci (QTLs). Coupled with gene expression data, we construct a systems-genetics network for gene discovery in potatoes. Importantly, we explore the genetic basis of heterosis in this population, especially for yield and male fertility heterosis. We find that positive heterotic effects of yield-related QTLs and negative heterotic effects of metabolite QTLs (mQTLs) contribute to yield heterosis. Additionally, we identify a PME gene with a dominance heterotic effect that plays an important role in male fertility heterosis. This study provides genetic resources for the potato community and will facilitate the application of heterosis in diploid potato breeding. An ongoing effort aims to transform the clonally propagated tetraploid potato to a seed-propagated diploid crop, but our understanding of it disomic inheritance is limited. Here, the authors report genetic basis of heterosis in the elite hybrid potato and identify a male fertility-related PME gene with dominance heterotic effect.