您好，欢迎访问浙江省农业科学院 机构知识库！
浙江省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Combined analysis of silk synthesis and hemolymph amino acid metabolism reveal key roles for glycine in increasing silkworm silk yields

文献类型： 外文期刊

作者： Chen, Xuedong 1 ; Ye, Aihong 1 ; Wu, Xuehui 1 ; Qu, Zhigang 2 ; Xu, Shiqing 2 ; Sima, Yanghu 2 ; Wang, Yujun 3 ; He, Ruimin 4 ; Jin, Fen 4 ; Zhan, Pengfei 5 ; Cao, Jinru 1 ; Zhou, Wenlin 1 ;

作者机构： 1.Zhejiang Acad Agr Sci, Inst Sericulture & Tea, Hangzhou 310021, Peoples R China

2.Soochow Univ, Med Coll, Sch Biol & Basic Med Sci, Suzhou 215123, Peoples R China

3.Beibu Gulf Univ, Coll Marine Sci, Guangxi Key Lab Beibu Gulf Marine Biodivers Conser, Qinzhou 535011, Peoples R China

4.Shengzhou Mulsun Biotech Co Ltd, Shengzhou 312400, Peoples R China

5.Huzhou Acad Agr Sci, Huzhou 313002, Peoples R China

关键词： Glycine; Formula feed; Silk synthesis

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：8.025； 五年影响因子：7.626 ）

ISSN： 0141-8130

年卷期： 2022 年 209 卷

页码：

收录情况： SCI

摘要： Rearing silkworms (Bombyx mori) using formula feed has revolutionized traditional mulberry feed strategies. However, low silk production efficiencies persist and have caused bottlenecks, hindering the industrial appli-cation of formula feed sericulture. Here, we investigated the effects of formula feed amino acid composition on silk yields. We showed that imbalanced amino acids reduced DNA proliferation, decreased Fib-H, Fib-L, and P25 gene expression, and caused mild autophagy in the posterior silk gland, reducing cocoon shell weight and ratio. When compared with mulberry leaves, Gly, Ala, Ser, and Tyr percentages of total amino acids in formula feed were decreased by 5.26%, while Glu and Arg percentages increased by 9.56%. These changes increased uric acid and several amino acids levels in the hemolymph of silkworms on formula feed. Further analyses showed that Gly and Thr (important synthetic Gly sources) increased silk yields, with Gly increasing amino acid conversion ef-ficiencies to silk protein, and reducing urea levels in hemolymph. Also, Gly promoted endomitotic DNA synthesis in silk gland cells via phosphoinositide 3-kinase (PI3K)/Akt/target of rapamycin (TOR) signaling. In this study, we highlighted the important role of Gly in regulating silk yields in silkworms.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：浙江省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台