Construction and Application of L-Penicillamine Molecular Imprinted Electrochemical Sensor Based on Covalent Organic Framework-JUZ2 Fixed Conformation
文献类型： 外文期刊
作者： Zhang Lian-Ming 1 ; Li Shu-Huai 1 ; Luo Kui 2 ; Dai Yu-Ning 2 ; Li Jian-Ping 2 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Anal & Test Ctr, Hainan Prov Key Lab Qual & Safety Trop Fruits & V, Haikou 571101, Hainan, Peoples R China
2.Guilin Univ Technol, Coll Chem & Bioengn, Key Lab New Technol Food Safety Testing, Guilin 541004, Peoples R China
关键词： Molecular imprinting; Chiral separation; Selectivity; Covalent organic framework; L-Penicillamine
期刊名称：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY （ 影响因子：1.193； 五年影响因子：0.987 ）
ISSN： 0253-3820
年卷期： 2022 年 50 卷 7 期
页码：
收录情况： SCI
摘要： The improvement of sensor selection recognition ability is crucial to the performance of molecular imprinted sensors. Herein, a molecularly imprinted polymer-based sensor was developed for L-penicillamine (L-Pen) detection based on covalent organic framework compounds COF-JUZ2. The molecular imprint chiral recognition sensor with efficient separation and recognition ability was constructed via selectively fixing the conformation of chiral molecules by COF-JUZ2 to increase the recognition sites. The sensor showed the optimal detection performance for L-Pen when using the mixed solution of ultrapure water, acetic acid and methanol (1 :1 : 8, V/V) as eluant and the COF-JUZ2-CS deposition time, electropolymerization cycle, eluent time and rebind time were 300 s, 15, 5 and 30 min, respectively. The sensor showed an excellent linear relationship with L-Pen concentration in the range of 1. 0 x 10(-15) to 1. 0 x 10(-9) mol/L, with a detection limit of 7. 91 x 10(-16) mol/L. Due to introduction of COF-JUZ2, the separation and recognition performance of the sensor for D-Pen and L-Pen was increased by 13.4 folds. The sensor was applied to determination of L-Pen in real sample, with recoveries of 92. 0% - 102. 0% .
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