The detection and elimination of flavin-containing monooxygenase 3 gene T329S mutation in the Beijing You chicken
文献类型： 外文期刊
作者： Chu, Qin 1 ; Zhang, Jian 1 ; Zhu, Shanshan 1 ; Zhang, Yao 1 ; Wang, Haihong 1 ; Geng, Ailian 1 ; Liu, Huagui 1 ;
作者机构： 1.Beijing Acad Agr & Forestry Sci, Inst Anim Husb & Vet Med, Beijing 100097, Peoples R China
关键词： flavin-containing monooxygenase 3;T329S;fishy taint;trimethylamine;Beijing You chicken
期刊名称：POULTRY SCIENCE （ 影响因子：3.352； 五年影响因子：3.679 ）
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收录情况： SCI
摘要： In this study, using a newly developed TaqMan-based real-time PCR method for the T329S mutation in the flavin-containing monooxygenase 3 (FM03) gene, a marker-assisted selective breeding program against the unfavorable T. allele was implemented in theBeijing You chicken breeding stock from 2010 to 2012. A total of 2,359 breeder candidate chickens were detected. After 1-generation culling in both males andfemales and 2-generation culling only in males, geno-typing results in 2013 showed that there still remained a low unfavorable allele frequency of 0.022 in this population. The results indicated that to ensure a complete eradication of the defective tainting mutation in FM03 out of the Beijing You population, more strict breeding and management schemes should be carried out in the future.
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