文献类型： 外文期刊
作者： Luo, Xiuqin 1 ; Li, Kaimian 1 ; Kai, Guoyin 2 ; Chen, Songbi 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Trop Crops Genet Resources Inst, Danzhou, Peoples R China
2.Shanghai Normal Univ, Coll Life & Environm Sci, Plant Biotechnol Lab, Shanghai, Peoples R China
关键词： Danshen;Tanshinones;Biosynthesis pathways;Mmetabolic regulation.
期刊名称：ASIAN JOURNAL OF CHEMISTRY （ 影响因子：0.355； 五年影响因子：0.293 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Tanshinones, a group of diterpenoids, are the important Moactive components of Danshen (Salvia miltiorrhiza Bunge) roots used as a well-known Chinese traditional medicine. They are detected to have many biological functions, such as antimicrobial, antiinflammatory, antioxidant, antineoplastic etc. and are widely used in the treatment of cardiovascular and cerebral vascular diseases. In the present paper, we reviewed the morphological characteristics, active components and chemical uses of Danshen in China and then summarize the pathways of tanshinones biosynthesis and biological functions. The metabolic regulation involved enhancing tanshinone production in Danshen is discussed, in which it will provide a new insight into understanding mechanism of biosynthesis of tanshinones.
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