Chemical characteristics and antithrombotic effect of chondroitin sulfates from sturgeon skull and sturgeon backbone
文献类型： 外文期刊
作者： Gui, Meng 1 ; Song, Juyi 1 ; Zhang, Lu 1 ; Wang, Shun 3 ; Wu, Ruiyun 1 ; Ma, Changwei 1 ; Li, Pinglan 1 ;
作者机构： 1.China Agr Univ, Coll Food Sci & Nutr Engn, Beijing Lab Food Qual & Safety, Beijing 100083, Peoples R China
2.Inst Agr Sci Jiangsu Changjiang River Bank Dist, Rugao 226541, Peoples R China
3.Beijing Fisheries Res Inst, Beijing 100068, Peoples R China
关键词： Sturgeon;Chondroitin sulfate;Anticoagulant;Anti-platelet aggregation;Thrombolysis
期刊名称：CARBOHYDRATE POLYMERS （ 影响因子：9.381； 五年影响因子：8.678 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Chondroitin sulfates (CSs) were extracted from sturgeon skull and backbone, and their chemical composition, anticoagulant, anti-platelet and thrombolysis activities were evaluated. The average molecular weights of CS from sturgeon skull and backbone were 38.5 kDa and 49.2 kDa, respectively. Disaccharide analysis indicated that the sturgeon backbone CS was primarily composed of disaccharide monosulfated in position four of the GalNAc (37.8%) and disaccharide monosulfated in position six of the GalNAc (59.6%) while sturgeon skull CS was primarily composed of nonsulfated disaccharide (74.2%). Sturgeon backbone CS showed stronger antithrombotic effect than sturgeon skull CS. Sturgeon backbone CS could significantly prolong activated partial thromboplastin time (APTT) and thrombin time (TT), inhibited ADP-induced platelet aggregation and dissolved platelet plasma clots in vitro. The results suggested that sturgeon backbone CS can be explored as a functional food with antithrombotic function. (C) 2015 Elsevier Ltd. All rights reserved.
- 相关文献
作者其他论文 更多>>
-
Optimizing vermiculite and sawdust ratios for enhancing composted green waste as a seedling substrate for cruciferous vegetables
作者：Chen, Yue;Zhang, Lu;Tong, Jing
关键词：Circular bioeconomy; Peat alternative; Organic waste amendment; Cruciferous vegetable nursery; Multivariate analysis
-
Insights into HIU enhancement of salt-reduced surimi gelation properties: Dual regulation of endogenous transglutaminase activation and protease inhibition
作者：Gao, Xia;Gui, Meng;Chen, Shengjun;Hu, Xiao;You, Juan;Yin, Tao;Hu, Yang;Xiong, Shanbai;Liu, Ru
关键词：High-intensity ultrasound; Salt-reduced surimi; Endogenous enzyme regulation; Gelation properties; Dynamic rheological properties
-
Multi-view hypergraph networks incorporating interpretability analysis for predicting lodging in corn varieties
作者：Wang, Kaiyi;Yang, Feng;Zhao, Xiangyu;Liu, Zhongqiang;Zhang, Qiusi;Li, Jinlong;Zhang, Dongfeng;Bai, Wenqin;Wang, Shun;Zhang, Yong;Wang, Kaiyi;Yang, Feng;Zhao, Xiangyu;Liu, Zhongqiang;Zhang, Qiusi;Li, Jinlong;Zhang, Dongfeng
关键词：Corn lodging classification; Multi-view hypergraph network; Graph interpretability
-
Complete genome sequence provides information on quorum sensing related spoilage and virulence of Aeromonas salmonicida GMT3 isolated from spoiled sturgeon
作者：Li, Jun;Gao, Liang;Zhang, Ying;Gui, Meng;Liu, Lei;Li, Jun;Tu, Mingxia;Rao, Yu;Rao, Lei;Liu, Lei;Li, Jun;Liu, Lei
关键词：Whole genome sequencing; Quorum sensing; Spoilage; Virulence; Aquatic products safety
-
Response surface methodology optimization on extraction and antioxidant activity evaluation of antioxidant peptide from enzymatic hydrolysates of sturgeon bone
作者：Zhang, Ying;Gui, Meng;Fan, Wei;Gao, Liang;Bu, Xianyong;Fan, Wei
关键词：Response surface methodology; Extraction condition; Fish byproducts; Antioxidant activity; Molecular weights
-
The underlying mechanism of bacterial spore germination: An update review
作者：Lyu, Fengzhi;Zhang, Tianyu;Wang, Yongtao;Zhao, Liang;Wu, Xiaomeng;Rao, Lei;Liao, Xiaojun;Gui, Meng;Rao, Lei
关键词：bacterial spores; nutrient germinants; high hydrostatic pressure; germination; molecular mechanisms
-
Southern rice black-streaked dwarf virus induces incomplete autophagy for persistence in gut epithelial cells of its vector insect
作者：Zhang, Lu;Liu, Wenwen;Wu, Nan;Wang, Hui;Wang, Xifeng;Zhang, Lu;Zhang, Zhongkai;Liu, Yule;Liu, Yule
关键词：
