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The antihyperlipidemic activities of enzymatic and acidic intracellular polysaccharides by Termitomyces albuminosus

文献类型： 外文期刊

作者： Zhao, Huajie 1 ; Li, Shangshang 2 ; Zhang, Jianjun 2 ; Che, Gen 3 ; Zhou, Meng 4 ; Liu, Min 2 ; Zhang, Chen 2 ; Xu, Nuo 2 ;

作者机构： 1.Beijing Acad Agr & Forestry Sci, Beijing Engn Res Ctr Edible Mushroom, Inst Plant & Environm Protect, Key Lab Urban Agr North,Minist Agr, Beijing 100097, Peoples R China

2.Shandong Agr Univ, Coll Life Sci, Tai An 271018, Shandong, Peoples R China

3.Shandong Acad Agr Sci, Jinan 250100, Peoples R China

4.Qual & Safety Monito

关键词： Antihyperlipidemic;Antioxidant;Hepatoprotective;Intracellular polysaccharides;Termitomyces albuminosus

期刊名称：CARBOHYDRATE POLYMERS （ 影响因子：9.381； 五年影响因子：8.678 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Two polysaccharides, EIPS and AIPS were obtained by the hydrolysis of IPS from Termitomyces albuminosus, and their pharmacological effects on blood lipid profiles metabolism and oxidative stress were investigated. The results demonstrated that EIPS was superior to IPS and AIPS on reducing hepatic lipid levels and preventing oxidative stress by improving serum enzyme activities (ALT, AST, and ALP), serum lipid levels (TC, TG, HDL-C, LDL-C and VLDL-C), hepatic lipid levels (TC and TG), and antioxidant status (SOD, GSH-Px, CAT, T-AOC, MDA, and LPO). These conclusions indicated that EIPS, AIPS and IPS might be suitable for functional foods and natural drugs on preventing the high-fat emulsion-induced hyperlipidemia. In addition, the monosaccharide compositions of IPS and its hydrolyzate were also processed. (C) 2016 Elsevier Ltd. All rights reserved.

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