文献类型： 外文期刊

作者： Pan, Xiaofan ¹ ; Zhang, Nan ² ; Hao, Shijuan ¹ ; Pei, Jiawei ¹ ; Tian, Yiling ¹ ; Guo, Runfang ¹ ;

作者机构： 1.Hebei Agr Univ, Food Sci & Technol, Baoding 071000, Hebei, Peoples R China

2.Hebei Acad Agr & Forestry Sci, Inst Biotechnol & Food Sci, Shijiazhuang 050051, Hebei, Peoples R China

关键词： Resistant starch; Sweet potato; Lipid-lowering; Intestinal microbiota

期刊名称：JOURNAL OF FUNCTIONAL FOODS （ 影响因子：4.0； 五年影响因子：4.9 ）

ISSN： 1756-4646

年卷期： 2025 年 128 卷

页码：

收录情况： SCI

摘要： Type 3 resistant starch (RS3) has been recognized for its potential to ameliorate obesity by modulating the intestinal microbiota. Our previous study confirmed that sweet potato RS3 (SP-RS3), which is readily obtainable from daily life, exhibited excellent resistance to gastrointestinal digestion. This study aimed to further investigate the effects of SP-RS3 on high-fat diet-induced obesity in mice. Results showed that SP-RS3 significantly reduced body weight gain and fat accumulation, reduced blood lipid level, alleviated oxidative stress, and improved liver function. Furthermore, SP-RS3 modulated the abundance and composition of the intestinal microbiota, decreasing the Firmicutes/Bacteroidetes ratio, and increasing the relative abundance of Bacteroides, Ruminococcus, Akkermansia, Bifidobacterium, while decreasing the relative abundance of Desulfovibrio and Helicobacter. In summary, SP-RS3 shows promising potential in regulating lipid metabolism by modulating intestinal microbiota