Bioaccessibility of Inorganic Arsenic in Rice: Probabilistic Estimation and Identification of Influencing Factors
文献类型： 外文期刊
作者： Zhou, Zheng 1 ; Yang, Guiling 2 ; Xun, Pengcheng 3 ; Wang, Qiang 2 ; Shao, Kan 1 ;
作者机构： 1.Indiana Univ, Sch Publ Hlth Bloomington, Dept Environm & Occupat Hlth, Bloomington, IN 47405 USA
2.Zhejiang Acad Agr Sci, State Key Lab Managing Biot & Chem Threats Qual, Key Lab Pesticide Residue Detect,Minist Agr,Inst, Minist Agr,Lab Hangzhou Risk Assessment Agr Prod, Hangzhou, Peoples R China
3.Indiana Univ, Sch Publ Hlth Bloomington, Dept Epidemiol & Biostat, Bloomington, IN USA
关键词： Rice; inorganic arsenic; bioaccessibility; in vitro extraction; exposure assessment; probabilistic assessment
期刊名称：FOOD REVIEWS INTERNATIONAL （ 影响因子：6.478； 五年影响因子：6.178 ）
ISSN： 8755-9129
年卷期：
页码：
收录情况： SCI
摘要： Bioaccessibility, defined as the fraction of inorganic arsenic (iAs) that becomes soluble in the GI tract and ready for absorption, is one of the determining factors that impacts the iAs exposure through rice consumption. The objective of this study is to, based on published data, quantitatively characterize the bioaccessibility of iAs in rice and identify its influencing factors. A total of 256 published papers were identified and reviewed, among which eight were selected as they provide adequate data to support the analyses of bioaccessibility and influencing factors. A meta-analysis was performed to characterize the probabilistic distribution of the bioaccessibility of iAs. A general regression analysis was performed to identify the influencing factors of the bioaccessibility. A beta distribution (a = 4.91, b = 1.85) with a mean and 90(th) percentile interval of 73% (43%, 95%) was estimated to adequately describe the iAs bioaccessibility in rice. The regression analysis shows that grain size (p-value < 0.001) and the inorganic-to-total proportion of arsenic (p-value < 0.001) are negatively associated with bioaccessibility, while milling status has no impact.
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