A novel 22-bp InDel within FGF7 gene is significantly associated with growth traits in goat
文献类型： 外文期刊
作者： Wu, Xian-feng 1 ; Liu, Yuan 1 ; Wang, Ying-gang 2 ; Zhang, Fu 2 ; Li, Wen-yang 1 ;
作者机构： 1.Fujian Acad Agr Sci, Fuzhou, Fujian, Peoples R China
2.Fujian Agr & Forestry Univ, Coll Anim Sci, Fuzhou, Fujian, Peoples R China
3.Fujian Acad Agr Sci, Inst Anim Husb & Vet, Fuzhou 350013, Fujian, Peoples R China
关键词： Goat; FGF7 gene; InDel; growth traits; marker-assisted selection (MAS)
期刊名称：ANIMAL BIOTECHNOLOGY （ 影响因子：3.7； 五年影响因子：3.3 ）
ISSN： 1049-5398
年卷期： 2023 年
页码：
收录情况： SCI
摘要： Fibroblast growth factor 7 (FGF7) is involved in lipid metabolism, which is considered as a candidate gene with close relation with muscle development by eGWAs and RNA-Seq analyses. To date, limited research has been conducted on the relationship between FGF7 gene and growth traits. The main objective of this work was to further investigate the association between novel InDel within FGF7 gene and growth traits in goat. Herein, FGF7 mRNA expression levels were investigated in various Fuqing goat tissues. We found that FGF7 gene was expressed in six adult goat tissues with the highest mRNA levels in adipose tissue. This result suggested that FGF7 gene might play a critical role in fat deposition. We also detected potential polymorphisms in Fuqing, Nubian and Jianyang Daer breeds. A 22-bp InDel polymorphism in FGF7 gene was detected in 396 goats and the three genotypes were designated as II, ID, and DD. Correlation analysis revealed that InDel polymorphism was significantly associated with growth traits (P < 0.05). Goats with genotypes ID and/or II had superior growth traits compared to those with genotype DD. In summary, our findings suggested that the 22-bp InDel within FGF7 gene could act as a molecular marker to improve the growth traits of goats in breeding programs.
- 相关文献
作者其他论文 更多>>
-
Relationship between Indel Variants within the JAK2 Gene and Growth Traits in Goats
作者：Wu, Xian-Feng;Xu, Qian;Li, Wen-Yang;Liu, Yuan;Wang, Ao;Wang, Ben-Zhi;Lan, Xian-Yong
关键词：goat; JAK2 gene; insertion/deletion; growth traits; marker-assisted selection (MAS)
-
Temporal Transcriptome Dynamics of Longissimus dorsi Reveals the Mechanism of the Differences in Muscle Development and IMF Deposition between Fuqing Goats and Nubian Goats
作者：Liu, Yuan;Wu, Xianfeng;Xu, Qian;Li, Wenyang;Lan, Xianyong
关键词：goat; transcriptome; growth; Longissimus dorsi muscle; development; genetics
-
Molecular and physiological mechanisms of tea (Camellia sinensis (L.) O. Kuntze) leaf and root in response to nitrogen deficiency
作者：Lin, Zheng-He;Chen, Chang-Song;Zhong, Qiu-Sheng;Ruan, Qi-Chun;Chen, Zhi-Hui;You, Xiao-Mei;Shan, Rui-Yang;Li, Xin-Lei;Zhang, Ya-Zhen;Zhao, Shui-Qing;Liu, Yuan
关键词：Tea; Nitrogen deficiency; Nitrogen metabolism; Transcriptome profile
-
Novel alternative splicing variants of ACOX1 and their differential expression patterns in goats
作者：Wu, Xian-Feng;Liu, Yuan;Gao, Cheng-Fang;Chen, Xin-Zhu;Zhang, Xiao-Pei;Li, Wen-Yang
关键词：
-
Identification of Resistance to Wet Bubble Disease and Genetic Diversity in Wild and Cultivated Strains of Agaricus bisporus
作者：Fu, Yongping;Wang, Xinxin;Li, Dan;Liu, Yuan;Song, Bing;Zhang, Chunlan;Wang, Qi;Li, Yu;Chen, Meiyuan;Zhang, Zhiwu
关键词：Agaricus bisporus;Mycogone perniciosa;highly resistant;SSR;population structure
-
A novel duplicated insertion/deletion (InDel) of the CPT1a gene and its effects on growth traits in goat
作者：Li, Wen-Yang;Liu, Yuan;Gao, Chen-Fang;Wu, Xian-Feng;Lan, Xian-Yong
关键词：Goat; CPT1a gene; insertion; deletion (InDel); growth traits; marker-assisted selection
-
A novel splice variant of goat CPT1a gene and their diverse mRNA expression profiles
作者：Wu, Xian-feng;Liu, Yuan;Huang, Qin-lou;Li, Wen-yang;Zhan, Jin-shun
关键词：Goat; CPT1a gene; alternative splicing; expression profiles; expression
