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Postnatal expression pattern of PPAR gamma gene in pigs

文献类型: 外文期刊

作者: Jiang, Junfang 1 ; Jiang, Yongqing 1 ; Zhu, Zhigang 2 ; Xu, Zirong 2 ;

作者机构: 1.Zhejiang Acad Agr Sci, Inst Anim Husb & Vet Sci, Hangzhou 310021, Zhejiang, Peoples R China

2.Zhejiang Univ, Anim Sci Coll, Hangzhou 310029, Zhejiang, Peoples R China

关键词: PPAR gamma;gene expression;fat deposition;pigs

期刊名称:TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES ( 影响因子:0.581; 五年影响因子:0.78 )

ISSN: 1300-0128

年卷期: 2009 年 33 卷 4 期

页码:

收录情况: SCI

摘要: PPAR gamma is a member of the peroxisome proliferator-activated receptor subfamily of nuclear hormone receptors. PPAR gamma has been showed to be a key regulator of adipocyte differentiation and lipid metabolism. The pattern of PPAR gamma gene expression in different growth stages and its relation with adipose deposition in pigs is studied. Fifteen female DurocxLandracexYorkshire pigs in 5 groups with 3 pigs in each grup, at live weight of 1, 30, 50, 70, and 90 kg were used to study the developmental gene expression of PPAR gamma in subcutaneous adipose tissue by means of semi-quantitative RTPCR. The results showed the PPAR gamma mRNA levels of porcine adipose tissue increased as pigs grew and deposited fat from 1 to 90 kg live weight (P < 0.05). The present data indicated a close positive correlation between the levels of PPAR gamma gene expression and the fat deposition rate in pigs. The experiment showed the total adipose weight increased significantly with body weight (P < 0.05).

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