Genomic analysis of rice stripe virus Zhejiang isolate shows the presence of an OTU-like domain in the RNA1 protein and a novel sequence motif conserved within the intergenic regions of ambisense segments of tenuiviruses
文献类型： 外文期刊
作者： Zhang, H.-M. 1 ; Yang, J. 2 ; Sun, H.-R. 2 ; Xin, X. 2 ; Wang, H.-D. 2 ; Chen, J.-P. 3 ; Adams, M. J.;
作者机构： 1.Zhejiang Acad Agr Sci, Inst Virol & Biotechnol, Hangzhou 310021, Peoples R China
2.Zhejiang Acad Agr Sci, Inst Virol & Biotechnol, Hangzhou 310021, Peoples R China; Gen Stn Plant Protect Zhejiang Prov, Hangzhou, Peoples R China; Rothamsted Res, Plant Pathol & Microbiol Dept, Harpenden, Herts, England
3.Zhejiang Acad Agr Sci, Inst Virol & Biotechnol, Hangzhou 31002
期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）
ISSN： 0304-8608
年卷期： 2007 年 152 卷 10 期
页码：
收录情况： SCI
摘要： The complete genome sequence of the four RNAs of rice stripe virus Zhejiang isolate was determined. In addition to polymerase modules, the pc1 protein encoded on RNA1 harbours an ovarian tumour (OTU) - like cysteine protease signature near its N-terminus, suggesting that the protein might yield the viral polymerase and one or more additional proteins by autoproteolytic cleavage and/or have deubiquitination activity. A novel inverted repeat sequence motif was found to be universal within the intergenic regions of ambisense genome segments of tenuiviruses, supporting the possibility that it may be functionally important, perhaps in regulating transcription termination.
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