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Azalomycin F-4a 2-ethylpentyl ester, a new macrocyclic lactone, from mangrove actinomycete Streptomyces sp 211726

文献类型： 外文期刊

作者： Yuan, Gan Jun 1 ; Hong, Kui 1 ; Lin, Hai Peng 1 ; Li, Jia 3 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

2.Hainan Med Coll, Dept Pharm, Haikou 571101, Peoples R China

3.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China

关键词： Streptomyces sp 211726;Azalomycin F-4a 2-ethylpentyl ester;Antifungal activity;Cytotoxity

期刊名称：CHINESE CHEMICAL LETTERS （ 影响因子：6.779； 五年影响因子：4.558 ）

ISSN： 1001-8417

年卷期： 2010 年 21 卷 8 期

页码：

收录情况： SCI

摘要： Azalomycin F-4a 2-ethylpentyl ester, a new 36-membered macrocyclic lactone antibiotic, was isolated from mangrove actinomycete Streptomyces sp. 211726. Its structure was elucidated on the basis of spectroscopic data. The compound showed broad-spectrum antifungal activity and moderate cytotoxicity against human colon tumor cell HCT-116. (C) 2010 Kui Hong. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  • 相关文献

[1]H-1 and C-13 assignments of two new macrocyclic lactones isolated from Streptomyces sp 211726 and revised assignments of Azalomycins F-3a, F-4a and F-5a. Yuan, Ganjun,Lin, Haipeng,Wang, Cheng,Hong, Kui,Yuan, Ganjun,Yuan, Ganjun,Hong, Kui,Liu, Yue,Li, Jia. 2011

[2]New Azalomycin F Analogs from Mangrove Streptomyces sp 211726 with Activity against Microbes and Cancer Cells. Yuan, Ganjun,Yuan, Ganjun,Hong, Kui,Lin, Haipeng,Yuan, Ganjun,Hong, Kui,She, Zhigang,Li, Jia. 2013

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