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Analysis on the Genetic Variation of KAP3.1 and KAP6.1 Gene in 6 Rabbit Populations

文献类型: 外文期刊

作者: Wu Tian-Wen 1 ; Li-Tang 2 ; Feng-Kai 3 ; Mao-Liu-Liu 1 ; Li Bi-Chun 1 ; Wu Xin-Sheng 1 ;

作者机构: 1.Yangzhou Univ, Anim Sci & Technol Coll, Yangzhou 225009, Peoples R China

2.Jinling Rabbit Farm, Nanjing 211103, Peoples R China

3.Fujian Acad Agr Sci, Rabbit Farm Inst Anim Sci & Vet, Fuzhou 350003, Peoples R China

关键词: Rabbit;KAP3.1 gene;KAP6.1 gene;genetic variation;Hardy-Weinberg equilibrium;China

期刊名称:JOURNAL OF ANIMAL AND VETERINARY ADVANCES ( 影响因子:0.365; 五年影响因子:0.359 )

ISSN: 1680-5593

年卷期: 2011 年 10 卷 7 期

页码:

收录情况: SCI

摘要: Researchers had scanned the complete CDS of rabbit KAP3.1 and KAP6.1 gene for the 1st time by PCR-SSCP and detected that their homology with mouse, chimpanzee, human, sheep and goat were >80%, suggesting that the two genes among different species kept high conservation in evolution. In this study, three genotypes and two alleles were found at KAP3.1-1 locus having one silent mutation (C91T) and there were two alleles and three genotypes in 5 un-translated region of KAP6.1 gene with the A 755 G mutation of the enhancer region. Herein, the distribution of these genotypes in all populations was consistent with the Hardy-Weinberg equilibrium and showed intermediate or low diversity. The result suggested a theoretical reference to the breeding of rabbit wool quality whether KAP3.1 and KAP6.1 gene could be a molecular marker or not.

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