1CRISPR/Cas9-mediated ApoE(-/-) and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels

作者： Huang, Lei; Cheng, Ying; Xu, Kui; Gao, Qian; Xia, Ying; Liu, Yang; Zhang, Xue; Mu, Yulian; Li, Kui; Hua, Zaidong; Xiao, Hongwei; Zheng, Xinming; Huang, Lei; SCI

机构： Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, Beijing 100193, Peoples R China; Hubei Acad Agr Sci, Inst Anim Sci & Vet Med, Hubei Key Lab Anim Embryo Engn & Mol Breeding, Wuhan 430064, Peoples R China; Hubei Acad Agr Sci, Inst Anim Sci & Vet Med, H;

来源：ONCOTARGET

关键词： cardiovascular disease dyslipidemia animal model multiple-gene knockout gene editing

年份：2017

2PCSK9-D374Y Suppresses Hepatocyte Migration through Downregulating Free Cholesterol Efflux Rate and Activity of Extracellular Signal-Regulated Kinase

作者： Huang, Lei; Cheng, Ying; Li, Kui; Mu, Yulian; SCI

机构： Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen Branch, Guangdong Lab Lingnan Modern Agr,Key Lab Livestock, Shenzhen 518120, Peoples R China; Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, 2 Yuanmingyuan West Rd, Beijing 100193, Peoples R China;

来源：ANALYTICAL CELLULAR PATHOLOGY

年份：2023