141An Extracytoplasmic Function Sigma/Anti-Sigma Factor System Regulates Hypochlorous Acid Resistance and Impacts Expression of the Type IV Secretion System in Brucella melitensis

作者： Li, Huoming; Hu, Sen; Yan, Xin; Yang, Yan; Liu, Wenxing; Bu, Zhigao; Li, Ganwu; Cai, Wentong; Bu, Zhigao; Cai, Wentong; SCI

机构： Chinese Acad Agr Sci, Harbin Vet Res Inst, Key Lab Vet Publ Hlth, State Key Lab Vet Biotechnol,Minist Agr, Harbin 150069, Peoples R China; Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Jiangsu, Peoples R China;

来源：JOURNAL OF BACTERIOLOGY

关键词： extracytoplasmic function sigma factor; ECF; gene regulation; type IV secretion; virulence; Brucella melitensis; brucella; virulence regulation

年份：2021

142The preclinical inhibitor GS441524 in combination with GC376 efficaciously inhibited the proliferation of SARS-CoV-2 in the mouse respiratory tract

作者： Shi, Yuejun; Yan, Yuanyuan; Jiao, Zhe; Guo, Fenglin; Fu, Zhen F.; Chen, Huanchun; Peng, Guiqing; Shuai, Lei; Wen, Zhiyuan; Wang, Chong; Bu, Zhigao; Shi, Yuejun; Yan, Yuanyuan; Jiao, Zhe; Guo, Fenglin; Fu, Zhen F.; Chen, Huanchun; Peng, Guiqing; Bu, Zhigao; SCI

机构： Huazhong Agr Univ, Coll Vet Med, State Key Lab Agr Microbiol, Wuhan, Peoples R China; Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Harbin, Peoples R China; Huazhong Agr Univ, Cooperat Innovat Ctr Sustainable Pig Prod, Key Lab Prevent Vet Med Hubei Prov, Wuhan, Peoples R China; Natl High Containment Lab Anim Dis Control & Prev, Harbin, Peoples R China;

来源：EMERGING MICROBES & INFECTIONS

关键词： SARS-CoV-2; mouse model; preclinical inhibitor; combined application; antiviral efficacy

年份：2021

143Proteomics Investigation of the Time Course Responses of RAW264.7 Macrophages to Infections With the Wild-Type and Twin-Arginine Translocation Mutant Strains of Brucella melitensis

作者： Yan, Xin; Hu, Sen; Yang, Yan; Xu, Da; Liu, Wenxing; Li, Ganwu; Cai, Wentong; Bu, Zhigao; Li, Ganwu; Cai, Wentong; Bu, Zhigao; SCI

机构： Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Key Lab Vet Publ Hlth,Minist Agr, Harbin, Peoples R China; Iowa State Univ, Coll Vet Med, Dept Vet Diagnost & Prod Anim Med, Ames, IA USA; Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China;

来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

关键词： Brucella melitensis; twin-arginine protein translocation; immune response; RAW264; 7 cell model; cytokines; nitric oxide; NO

年份：2021

144Comparison of transcriptional change of B. melitensis M5-90 after macrophage infection highlights the role of ribosome gene L31 in virulence

作者： Xu, Da; Zhao, Jianlong; Jiang, Liying; Song, Jiabao; Zong, Shucheng; Yan, Xin; Zhang, Huitong; Hu, Sen; Bu, Zhigao; Xu, Da; Liu, Haican; SCI

机构： Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Key Lab Vet Publ Hlth,Minist Agr, Harbin 150069, Peoples R China; Chinese Ctr Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Collaborat Innovat Ctr Diag & Treatment Infect Di, Natl Inst Communicable Dis Control & Prevent, Beijing 102206, Peoples R China;

来源：VETERINARY MICROBIOLOGY

关键词： Ribosome gene L31; Brucella melitensis; Virulence; RNA-seq; Intracellular

年份：2021

145Characterization of Anti-p54 Monoclonal Antibodies and Their Potential Use for African Swine Fever Virus Diagnosis

作者： Tesfagaber, Weldu; Wang, Lulu; Tsegay, Ghebremedhin; Hagoss, Yibrah Tekle; Zhang, Zhenjiang; Zhang, Jiwen; Huangfu, Haoyue; Xi, Fei; Li, Fang; Sun, Encheng; Bu, Zhigao; Zhao, Dongming; Tesfagaber, Weldu; Tsegay, Ghebremedhin; SCI

机构： Chinese Acad Agr Sci, State Key Lab Vet Biotechnol, Natl High Containment Facil Anim Dis Control & Pr, Harbin Vet Res Inst, Harbin 150069, Peoples R China; Hamelmalo Agr Coll, Dept Vet Sci, Keren 397, Eritrea;

来源：PATHOGENS

关键词： African swine fever virus; p54; monoclonal antibodies; competitive ELISA; diagnosis

年份：2021

146Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020

作者： Sun, Encheng; Zhang, Zhenjiang; Wang, Zilong; He, Xijun; Zhang, Xianfeng; Wang, Lulu; Wang, Wenqing; Huang, Lianyu; Xi, Fei; Huangfu, Haoyue; Tsegay, Ghebremedhin; Huo, Hong; Sun, Jianhong; Tian, Zhijun; Xia, Wei; Li, Fang; Liu, Renqiang; Guan, Yuntao; Zhao, Dongming; Bu, Zhigao; Yu, Xuewu; SCI

机构： Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Natl High Containment Facil Anim Dis Control & Pr, Harbin 150069, Peoples R China; Inner Mongolia Univ Nationalities, Coll Anim Sci & Technol, Tongliao 028000, Peoples R China;

来源：SCIENCE CHINA-LIFE SCIENCES

关键词： African swine fever virus; natural mutant; non-hemadsorbing; lower virulent

年份：2021

147A novel linear and broadly neutralizing peptide in the SARS-CoV-2 S2 protein for universal vaccine development

作者： Li, Tuofan; Kan, Qiuqi; Wan, Zhimin; Xie, Quan; Yang, Yi; Shao, Hongxia; Li, Xiangdong; Qin, Aijian; Ye, Jianqiang; Li, Tuofan; Kan, Qiuqi; Wan, Zhimin; Xie, Quan; Yang, Yi; Shao, Hongxia; Li, Xiangdong; Qin, Aijian; Ye, Jianqiang; Li, Tuofan; Kan, Qiuqi; Xie, Quan; Yang, Yi; Shao, Hongxia; Li, Xiangdong; Qin, Aijian; Ye, Jianqiang; Li, Tuofan; Kan, Qiuqi; Wan, Zhimin; Xie, Quan; Yang, Yi; Shao, Hongxia; Li, Xiangdong; Qin, Aijian; Ye, Jianqiang; Ge, Jinying; Bu, Zhigao; Bu, Zhigao; Yuan, Mengqi; Liu, Pinghuang; Huang, Yao; Ye, Lilin; SCI

机构： Yangzhou Univ, Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Jiangsu, Peoples R China; Yangzhou Univ, Coll Vet Med, Key Lab Jiangsu Prevent Vet Med, Key Lab Avian Prevent Med,Minist Educ, Yangzhou 225009, Jiangsu, Peoples R China; Yangzhou Univ, Joint Int Res Lab Agr & Agri Prod Safety, Minist Educ China, Yangzhou 225009, Jiangsu, Peoples R China; Yangzhou Univ, Inst Agr Sci & Technol Dev, Yangzhou 225009, Jiangsu, Peoples R China; Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Harbin 150069, Peoples R China; Natl High Containment Lab Anim Dis Control & Prev, Harbin 150069, Peoples R China; China Agr Univ, Coll Vet Med, Beijing 100193, Peoples R China; Ctr Dis Control & Prevent, Yangzhou 225009, Jiangsu, Peoples R China; Third Mil Med Univ, PLA, Inst Immunol, Chongqing 400038, Peoples R China;

来源：CELLULAR & MOLECULAR IMMUNOLOGY

年份：2021

148Rapid and ultra-sensitive detection of African swine fever virus antibody on site using QDM based-ASFV immunosensor (QAIS)

作者： Li, Jiahao; Zhang, Yue; Shan, Yanke; Liu, Fei; Li, Jiahao; Zhang, Yue; Shan, Yanke; Liu, Fei; Bai, Yun; Xie, Qingyun; Zhang, Lei; Hua, Lizhong; Xiong, Qiyan; Shao, Guoqing; Feng, Zhixin; Li, Fang; Bu, Zhigao; Zhao, Dongming; SCI

机构： Nanjing Agr Univ, Minist Educ, Joint Int Res Lab Anim Hlth & Food Safety, Nanjing 210095, Jiangsu, Peoples R China; Nanjing Agr Univ, Single Mol Nanometry Lab Sinmolab, Nanjing 210095, Jiangsu, Peoples R China; Jiangsu Acad Agr Sci, Inst Vet Med, Key Lab Vet Biol Engn & Technol, Minist Agr, Nanjing 210014, Peoples R China; Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Harbin 150069, Peoples R China;

来源：ANALYTICA CHIMICA ACTA

关键词： African swine fever virus (ASFV) antibodies; Dual quantum dot microsphere (QDM) probes; Pre-incubation; QDM based-ASFV immunosensor (QAIS); Clinical samples; On-site testing

年份：2022

149Lateral Flow Assay for the Detection of African Swine Fever Virus Antibodies Using Gold Nanoparticle-Labeled Acid-Treated p72

作者： Zhu, Wenzhuang; Meng, Kaiwen; Zhang, Yueping; Meng, Geng; Bu, Zhigao; Zhao, Dongming; SCI

机构： China Agr Univ, Coll Vet Med, Beijing, Peoples R China; Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Natl High Containment Facil Anim Dis Control & Pr, Harbin, Peoples R China;

来源：FRONTIERS IN CHEMISTRY

关键词： African swine fever virus; gold nanoparticle; lateral flow assay; p72; acid treatment

年份：2022

150Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

作者： Wang, Xinxin; Wen, Zhiyuan; Cao, Huizhen; Luo, Jie; Shuai, Lei; Wang, Chong; Ge, Jinying; Wang, Xijun; Bu, Zhigao; Wang, Jinliang; SCI

机构： Chinese Acad Agr Sci, Harbin Vet Res Inst, State Key Lab Vet Biotechnol, Harbin, Peoples R China;

来源：JOURNAL OF VIROLOGY

关键词： rabies virus; SARS-CoV-2; mGluR2; internalization; TfR1

年份：2023