Syntheses of novel fluoroquinolone compounds

文献类型: 外文期刊

第一作者: Li, JY

作者: Li, JY;Lu, RH;Yang, AM;Zhang, JY

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期刊名称:HETEROCYCLIC COMMUNICATIONS ( 影响因子:1.12; 五年影响因子:1.045 )

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收录情况: SCI

摘要: A series of 1-substituted-6-fluoro-7-(1-(4-((Z)-2-(2-aminothiazol -4-yl)-2-methoxyi-minoacetyl)piperazinyl))-1,4-dihydro-4-oxo-3-quinoline carboxylic acid has been prepared and evaluated for antibacterial. activity. These compounds were prepared by the combination of 1-substituted- 6-fluoro-7- piperazinyl- 1,4-dihydro- 4-oxo-3-quinolinecarboxylic acid and S-2-benzo- thiazoyl-(Z)-2-(2-aminothiazol-4-yl)-2-methoxyimino acetate(MAEM) under the condition of Schotten-Baumann. The title compounds are confirmed with NMR,UV, IR, FAB-MS, et al.

分类号: O6

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