Genomic functional annotation and comparative analysis of ABC transporter protein family genes in nine types of Chironomidae insects

文献类型： 外文期刊

第一作者： Liu, Wenbin

作者： Liu, Wenbin;Zhou, Anmo;Shao, Ziming;Nie, Jiaxin;Ge, Xinyu;Yan, Chuncai;Gao, Shaobo;Wang, Yiwen;Wang, Yiwen

作者机构：

关键词： ATP-binding cassette transporter; No biting midges; Gene annotation; Environmental adaptability

期刊名称：BMC GENOMICS （ 影响因子：3.7； 五年影响因子：4.2 ）

ISSN： 1471-2164

年卷期： 2025 年 26 卷 1 期

页码：

收录情况： SCI

摘要： BackgroundThe ABC (ATP-binding cassette) transporter family constitutes one of the most extensive transmembrane transporter gene families found across all realms of life. In insects, ABC transporters are crucial for processes such as nutrient metabolism, regulating metamorphosis, and detoxifying xenobiotics. Chironomidae, a diverse aquatic insect group of significant ecological importance that does not bite, has lacked comprehensive annotation of ABC transporters, with the exception of our recent work on Propsilocerus akamusi. In this study, we broaden the annotation by detecting ABC transporter genes across eight additional Chironomidae species, which include all accessible genomes.ResultsA total of 454 ABC transporter genes were annotated across the eight species, categorized into eight distinct subfamilies: 67 belonging to the ABCA subfamily, 45 to ABCB, 105 to ABCC, 13 to ABCD, eight to ABCE, 23 to ABCF, 114 to ABCG, and 78 to ABCH. Phylogenetic analysis using Drosophila melanogaster as an external reference revealed clear orthologous relationships for most Chironomidae ABC transporters, except for a notable expansion of the ABCH subfamily.ConclusionsThis research offers crucial understanding of the evolutionary processes and physiological roles played by ABC transporters within the Chironomidae species, offering a foundation for understanding their role in the environmental adaptability of these species.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序