Multi-mode probe based on dual colorimetric and photothermal later flow immunoassay for the ultrasensitive determination of benzo[a]pyrene in vegetable oils

文献类型： 外文期刊

第一作者： Yuan, Yuting

作者： Yuan, Yuting;Tang, Xiaoqian;Zhang, Liangxiao;Zhang, Qi;Ma, Fei;Li, Peiwu;Yuan, Yuting;Tang, Xiaoqian;Zhang, Liangxiao;Zhang, Qi;Ma, Fei;Li, Peiwu;Yuan, Yuting;Tang, Xiaoqian;Zhang, Liangxiao;Zhang, Qi;Ma, Fei;Li, Peiwu;Yuan, Yuting;Tang, Xiaoqian;Zhang, Liangxiao;Zhang, Qi;Ma, Fei;Li, Peiwu;Tang, Xiaoqian;Zhang, Liangxiao;Zhang, Qi;Ma, Fei;Li, Peiwu;Li, Peiwu

作者机构：

关键词： Benzo[ a ]pyrene; Nanozymes; Multi mode; Lateral flow immunoassay; Hazardous substances; Vegetable oils

期刊名称：FOOD CHEMISTRY （ 影响因子：9.8； 五年影响因子：9.7 ）

ISSN： 0308-8146

年卷期： 2025 年 482 卷

页码：

收录情况： SCI

摘要： Lateral flow immunoassays (LFIA) have been acknowledged as the promising on-site screening method for food survey. Monoclonal antibodies against benzo[a]pyrene (BaP) conjugated with enzyme-mimetic probes, a multi mode LIFA strips were systemically constructed and evaluated. The PBNPs@mAbs based LFIA could conduct triple measurement in 14 min. This assay had good limit of detections (LODs of 0.057, 0.035, and 0.106 mu g kg-1), ultra calibration ranges (0.23-500, 0.076-56, 0.69-167 mu g kg-1), and the recoveries ranging from 86 % to 105 % with the precision less than 12 %. Compared with the reported methods, the LODs were 175-, 285-and 94-folds enhanced, and dynamic linear ranges were greatly expanded. Finally, this novel PBNPs@mAbs LFIA assay with simplicity, rapidity, and sensitivity was successfully utilized for the determination of BaP in vegetable oils, which could be used as a superior enzyme-mimetic on-site analytic platform in food safety.

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