Biochemical responses in gills of rainbow trout exposed to propiconazole

文献类型： 外文期刊

第一作者： Li, Zhi-Hua

作者： Li, Zhi-Hua;Zlabek, Vladimir;Grabic, Roman;Li, Ping;Randak, Tomas;Li, Zhi-Hua;Li, Ping

作者机构：

关键词： catalase: 9001-05-2;EC 1.11.1.6;superoxide dismutase: 9054-89-1;EC 1.15.1.1;reactive oxygen species: ROS;7782-44-7;propiconazole: 60207-90-1;pesticide;fungicide;sodium ion-potassium ion-ATPase: EC 3.6.3.9;oxidative stress;surface water;enzyme activity;ground water;biochemical response

期刊名称：CENTRAL EUROPEAN JOURNAL OF BIOLOGY （ 影响因子：1.016； 五年影响因子：0.975 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： The aim of this study is to investigate the toxic effect of PCZ, a triazole fungicide commonly present in surface and ground water, on the ROS defense system and Na+-K+-ATPase in gills of rainbow trout exposed to sublethal concentrations (0.2, 50 and 500 mu g L-1) for 7, 20 and 30 days. After prolonged exposure of PCZ at higher test concentrations (50 and 500 mu g L-1), oxidative stress was apparent as reflected by the significant higher ROS levels in fish gill, as well as the significant inhibition of SOD and CAT activities. In addition, Na+-K+-ATPase activities were significantly lower than those of the control with increasing PCZ concentration and prolonged exposure period. The results of this study indicate that chronic exposure to PCZ has altered multiple physiological indices in fish gill; however, before these parameters are used as unique biomarkers for monitoring residual pharmaceuticals in aquatic environments, more detailed laboratory experiments need to be performed.

分类号： Q

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