Transmission of avian H9N2 influenza viruses in a murine model

文献类型: 外文期刊

第一作者: Wu, Rui

作者: Wu, Rui;Liu, Zewen;Liang, Wangwang;Yang, Keli;Xiong, Zhongliang;Xu, Diping;Sui, Zhiwei;Wu, Rui;Xu, Diping

作者机构:

关键词: Avian influenza virus;H9N2 subtype;Transmission;Contact spread;Droplet spread

期刊名称:VETERINARY MICROBIOLOGY ( 影响因子:3.293; 五年影响因子:3.599 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: Avian H9N2 influenza viruses have circulated widely in domestic poultry around the world, resulting in occasional transmission of virus from infected poultry to humans. However, it is unknown whether H9N2 influenza virus has acquired the ability to be transmitted from human to human. Here, we report that mouse-adapted H9N2 influenza viruses can replicate efficiently and are lethal for several strains of mice. To evaluate the transmissibility of mouse-adapted H9N2 influenza viruses, we carried out transmission studies in mice using both contact and respiratory droplet routes. Our results indicate that mouse-adapted H9N2 influenza viruses can replicate efficiently and be transmitted between mice. This suggests that once H9N2 influenza viruses adapt to new host, they should present potential public health risks, therefore, urgent attention should be paid to H9N2 influenza viruses.

分类号: S8

  • 相关文献

[1]Sequence analysis of the haemagglutinin genes of H9N2 avian influenza viruses isolated in China during 1996 to 2011. Dai, Yin,Zhao, Ruihong,Hu, Xiaomiao,Zhang, Danjun,Wang, Junjun,Xu, Fazhi. 2012

[2]Sequence and phylogenetic analysis of hemagglutinin genes of H9N2 influenza viruses isolated from chicken in China from 2013 to 2015. Su Xiao-na,Xie Qing-mei,Chen Wei-guo,Bi Ying-zuo,Chen Feng,Su Xiao-na,Xie Qing-mei,Chen Feng,Su Xiao-na,Xie Qing-mei,Chen Feng,Liao Chang-tao,Yan Zhuan-qiang. 2016

[3]Development of blocking ELISA for detection of antibodies against H9N2 avian influenza viruses. Li, Zejun.

[4]Single-amino-acid mutation in the HA alters the recognition of H9N2 influenza virus by a monoclonal antibody. Ping, Jihui,Li, Chengjun,Deng, Guohua,Jiang, Yongping,Tian, Guobin,Bu, Zhigao,Chen, Hualan,Ping, Jihui,Zhang, Shuxia. 2008

[5]H9N2 avian influenza virus-derived natural reassortant H5N2 virus in swan containing the hemagglutinin segment from Eurasian H5 avian influenza virus with an in-frame deletion of four basic residues in the polybasic hemagglutinin cleavage site. Wang, Youling,Yuan, Xiaoyuan,Qi, Lihong,Zhang, Yuxia,Xu, Huaiying,Yang, Jinxing,Ai, Wu,Song, Minxun,Li, Feng,Qi, Wenbao,Liao, Ming,Wang, Dan,Li, Feng,Li, Feng.

[6]Antigenic and genetic analysis of the H9N2 avian influenza viruses isolated in China. Li, CJ,Tian, GB,Li, YB,Yu, DD,Yu, KZ,Chen, HL. 2004

[7]Special Issue: Research status of clubroot (Plasmodiophora brassicae) on cruciferous crops in China. Chai, A. L.,Xie, X. W.,Shi, Y. X.,Li, B. J.. 2014

[8]Evolution analysis of the matrix (M) protein genes of 17 H9N2 chicken influenza viruses isolated in northern China during 1998-2008. Huang, Yanyan,Hu, Beixia,Zhang, Xiumei,Wen, Xintian,Cao, Sanjie,Xu, Dong,Khan, Mazhar I.. 2009

[9]High prevalence and widespread distribution of multi-resistant Escherichia coli isolates in pigs and poultry in China. Jiang, Hong-Xia,Chen, Zhang-Liu,Wang, Xiu-Mei,Chen, Ji-Rong,Liu, Ya-Hong,Liao, Xiao-Ping,Liu, Jian-Hua,Zeng, Zhen-Ling,Lue, Dian-Hong. 2011

[10]Molecular characterization of a novel defective DNA isolated from tobacco tissues infected with tobacco leaf curl virus. Zhou, XP,Xie, Y,Zhang, ZK,Qi, YJ,Wu, JJ. 2001

[11]Design of an Electric Control System for Plastic Pipe Automatic Conveyor Line. Jiang, Rui,Huang, Hui,Zhang, Ying. 2012

[12]Experimental transmission of an unnamed bovine Babesia by Hyalomma spp., Haemaphysalis longicornis and Boophilus microplus. Luo, JX,Chen, FY,Lu, WS,Guan, GQ,Ma, ML,Yin, H. 2003

[13]Bioassay evidence for the transmission of WSSV by the harpacticoid copepod Nitocra sp.. Zhang, Jia-Song,Dong, Shuang-Lin,Dong, Yun-Wei,Tian, Xiang-Li,Hou, Chun-Qiang,Zhang, Jia-Song. 2008

[14]Assessment of the role of brine shrimp Artemia in white spot syndrome virus (WSSV) transmission. Zhang, Jia-Song,Dong, Shuang-Lin,Dong, Yun-Wei,Tian, Xiang-Li,Zhang, Jia-Song,Cao, Yi-Cheng,Li, Zuo-Jia,Yan, Dong-Chun.

[15]Dissemination of Plasmodiophora brassicae in livestock manure detected by qPCR. Chai, A. L.,Li, J. P.,Xie, X. W.,Shi, Y. X.,Li, B. J..

[16]Location and transmission of QTL for multiple traits in the pedigree of soybean cultivars. Yang, RunQing,Qin, Jun,Liu, ZhangXiong,Zhang, YongFang,Li, YingHui,Guan, RongXia,Chang, RuZhen,Qiu, LiJuan,Qin, Jun,Jiang, ChengXi,Li, WenBin.

[17]Association of different endosymbionts with the whitefly species Bemisia tabaci and Trialeurodes vaporariorum (Sternorrhyncha : Aleyrodidae). Tan, ZJ,Xie, BY,Xiao, QM,Yang, YH,Wan, FH,Huang, SW.

[18]Comparative genomic analysis of the IId subtype family of Cryptosporidium parvum. Feng, Yaoyu,Li, Na,Feng, Yaoyu,Liu, Guangyuan,Li, Na,Roellig, Dawn M.,Kelley, Alyssa,Amer, Said,Xiao, Lihua,Amer, Said,Xiao, Lihua,Zhang, Longxian.

[19]Epidemiology of toxoplasmosis: role of the tick Haemaphysalis longicornis. Zhou, Yongzhi,Zhang, Houshuang,Cao, Jie,Gong, Haiyan,Zhou, Jinlin,Zhou, Jinlin. 2016

[20]Identification of a protein associated with circulative transmission of Barley yellow dwarf virus from cereal aphids, Schizaphis graminum and Sitobion avenae. Zhou, GH.

作者其他论文 更多>>