Association between IGF-IR, m-calpain and UCP-3 gene polymorphisms and growth traits in Nanyang cattle

文献类型: 外文期刊

第一作者: Zhang, Runfeng

作者: Zhang, Runfeng;Li, Xiaofeng

作者机构:

关键词: Beef cattle;Growth traits;Association analysis

期刊名称:MOLECULAR BIOLOGY REPORTS ( 影响因子:2.316; 五年影响因子:2.357 )

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收录情况: SCI

摘要: The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain/HhaI, and UCP-3/BglI polymorphisms and to determine associations between these polymorphisms and growth traits in Chinese indigenous cattle breeds. Genotyping was performed on 321 animals including 135 Nanyang, 80 Qinchuan, and 106 Jiaxian cattle. No significant differences in growth traits were observed between the genotypes of IGF-IR/TaqI polymorphism in Nanyang cattle. The m-calpain/HhaI, and UCP-3/BglI polymorphisms were associated with body weight, withers height, and body length of 6months (P<0.05 or P<0.01), body length of 18months (P<0.05), and body length and heart girth of 24months (P<0.01) in Nanyang cattle. In addition, Nanyang cattle aged 12months with AB genotype of m-calpain/HhaI polymorphism had higher body length and heart girth than those with BB genotype (P<0.01). The withers height were greater (P<0.01) in Nanyang cattle aged 12months with genotype AB of UCP-3/BglI polymorphism than those with genotype BB. The Nanyang cattle aged 24months with genotype AA had higher withers height than those with genotype BB (P<0.05). In conclusion, the m-calpain/HhaI and UCP-3/BglI polymorphisms may be used as DNA markers for selection in the breeding process of Nanyang cattle.

分类号: Q7

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