Recent advances in the exploration and discovery of SARS-CoV-2 inhibitory peptides from edible animal proteins

文献类型： 外文期刊

第一作者： Kong, Xiaoyue

作者： Kong, Xiaoyue;Liu, Xingquan;Kong, Xiaoyue;Wang, Wei;Bai, Kaiwen;Wu, Yi;Qi, Qianhui;Zhong, Yizhi;Xie, Junran;Wang, Nan;Zhang, Yu

作者机构：

关键词： efficacy; mechanisms; peptides derived from animal proteins; SARS-CoV-2; computer-aided design methods; drug delivery strategies

期刊名称：FRONTIERS IN NUTRITION （ 影响因子：5.0； 五年影响因子：5.7 ）

ISSN： 2296-861X

年卷期： 2024 年 11 卷

页码：

收录情况： SCI

摘要： The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), is spreading worldwide. Although the COVID-19 epidemic has passed its peak of transmission, the harm it has caused deserves our attention. Scientists are striving to develop medications that can effectively treat COVID-19 symptoms without causing any adverse reactions. SARS-CoV-2 inhibitory peptides derived from animal proteins have a wide range of functional activities in addition to safety. Identifying animal protein sources is crucial to obtaining SARS-CoV-2 inhibitory peptides from animal sources. This review aims to reveal the mechanisms of action of these peptides on SARS-CoV-2 and the possibility of animal proteins as a material source of SARS-CoV-2 inhibitory peptides. Also, it introduces the utilization of computer-aided design methods, phage display, and drug delivery strategies in the research on SARS-CoV-2 inhibitor peptides from animal proteins. In order to identify new antiviral peptides and boost their efficiency, we recommend investigating the interaction between SARS-CoV-2 inhibitory peptides from animal protein sources and non-structural proteins (Nsps) using a variety of technologies, including computer-aided drug approaches, phage display techniques, and drug delivery techniques. This article provides useful information for the development of novel anti-COVID-19 drugs.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序