文献类型： 外文期刊
第一作者： Deng, Mingqin
作者： Deng, Mingqin;Basak, Patangal;Song, Jiajia;Suo, Huayi;Deng, Mingqin;Song, Jiajia;Suo, Huayi;Zhang, Yuhong;Suo, Huayi
作者机构：
关键词： Nicotine; Nicotine-degrading microorganisms; Biodegradation; Human health
期刊名称：TOXICON （ 影响因子：2.4； 五年影响因子：2.5 ）
ISSN： 0041-0101
年卷期： 2025 年 254 卷
页码：
收录情况： SCI
摘要： Nicotine is a toxic and addictive alkaloid found in tobacco and tobacco products that is harmful to human health and is an environmental pollutant. Nicotine-degrading microorganisms are unique microorganisms with the ability to use nicotine molecules as their sole source of nitrogen and carbon needed for growth. They are capable of degrading nicotine into less toxic or non-toxic metabolites. This review describes the environment's primary nicotine contamination sources and potential hazards. It also summarizes various types of nicotine-degrading microorganisms, their optimal culture conditions, and degradation efficiency. Four different catabolic pathways of nicotine in microorganisms are discussed, and the applications of nicotine-degrading microorganisms in different fields, such as the tobacco, pharmaceutical, and environmental protection industries, are outlined. This review describes the hazards of nicotine and the current research and application of nicotine-degrading microorganisms. It provides a theoretical reference for future research on nicotine-degrading microorganisms and their applications.
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