文献类型： 外文期刊
第一作者： Hu, Haifei
作者： Hu, Haifei;Li, Risheng;Zhao, Junliang;Hu, Haifei;Li, Risheng;Zhao, Junliang;Hu, Haifei;Li, Risheng;Zhao, Junliang;Li, Risheng;Batley, Jacqueline;Edwards, David;Edwards, David
作者机构：
关键词： pangenome; plant; genome variation; bioinformatic pipeline; data analysis and visualization
期刊名称：GENOME BIOLOGY AND EVOLUTION （ 影响因子：3.3； 五年影响因子：3.5 ）
ISSN： 1759-6653
年卷期： 2024 年 16 卷 4 期
页码：
收录情况： SCI
摘要： A pangenome captures the genomic diversity for a species, derived from a collection of genetic sequences of diverse populations. Advances in sequencing technologies have given rise to three primary methods for pangenome construction and analysis: de novo assembly and comparison, reference genome-based iterative assembly, and graph-based pangenome construction. Each method presents advantages and challenges in processing varying amounts and structures of DNA sequencing data. With the emergence of high-quality genome assemblies and advanced bioinformatic tools, the graph-based pangenome is emerging as an advanced reference for exploring the biological and functional implications of genetic variations.
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