Polyoxometalate-induced hydrogel with in situ nano/bioenzyme cascade reaction generating intensive and long-lasting glow-type chemiluminescence

文献类型: 外文期刊

第一作者: Khan, Habib

作者: Khan, Habib;Yang, Jinlan;Wang, Meng;Yang, Li;Zhang, Huifeng;Sun, Jilai

作者机构:

关键词: Hydrogel; Long-lasting chemiluminescent; Polyoxometalate; Nanozyme; Bioenzyme; Cascade reactions

期刊名称:CHEMICAL ENGINEERING JOURNAL ( 影响因子:13.2; 五年影响因子:13.5 )

ISSN: 1385-8947

年卷期: 2024 年 499 卷

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收录情况: SCI

摘要: In this study, we introduce a straightforward one-step, in-situ strategy for the generation of long-lasting and intensive glow-type chemiluminescence (CL) for glucose sensing in biological samples. The approach involves the utilization of polyoxometalate (POM)-induced alginate hydrogel, which effectively encapsulates both the catalysts (POM and glucose oxidase (GOx)) and the CL reagent (luminol) in solution. Leveraging the peroxidase-like nanozyme properties of POM and the bioenzyme GOx, embedded within the nano-sized pores of the hydrogel, we achieve intensive and persistent CL emission lasting over 16 h. The POM-hydrogel-based CL system demonstrates remarkable storage stability and reproducibility, and it can be applied to quantitatively determine serum glucose with high accuracy. Our study indicates that the POM-hydrogel platform, supporting and confining nano/bioenzyme cascade reactions, holds great promise for the establishment of glow-type CL systems, which could be of great value in various fields of CL biosensing and imaging.

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