Determination of Bisphenol Compounds and the Bioaccumulation after Co-Exposure with Polyethylene Microplastics in Zebrafish

文献类型： 外文期刊

第一作者： Xue, Moyong

作者： Xue, Moyong;Jia, Ming;Li, Jing;Gu, Xu;Xue, Moyong;Francis, Frederic;Xue, Moyong;Qin, Yuchang;Yao, Ting

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关键词： bisphenol compounds; microplastic; co-exposure; bioaccumulation

期刊名称：TOXICS （ 影响因子：4.1； 五年影响因子：4.6 ）

ISSN：

年卷期： 2024 年 12 卷 10 期

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收录情况： SCI

摘要： Knowledge regarding the combined toxicity mechanism of bisphenol compounds and microplastics (MPs) on organisms remains limited. In this study, we first developed an accurate and sensitive method to simultaneously quantify two bisphenol compounds and evaluate their accumulation and tissue distribution after co-exposure with MPs in zebrafish. Then, we determined the bioaccumulation potential of bisphenol A (BPA) and bisphenol S (BPS) in adult zebrafish in the absence and presence of MPs. Bisphenol compounds were found to accumulate in different tissues of zebrafish, with BPS showing lower accumulation levels compared to BPA. Importantly, we discovered that the presence of MPs could exacerbate the accumulation of bisphenol compounds in biological tissues. These findings highlight the enhanced bioavailability and risk posed by the co-exposure of bisphenol compounds and MPs, underscoring the need for further investigation into their combined environmental and biological health impacts.

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