文献类型： 外文期刊
第一作者： Sun, Haijun
作者： Sun, Haijun;Liao, Jialong;He, Linjuan;Wan, Boyang;Yin, Jingdong;Zhang, Xin;Chen, Meixia;Yin, Jingdong;Zhang, Xin
作者机构：
关键词： foetal skeletal muscle development; gut microbiota; maternal exercise; maternal nutrition; metabolic disorders
期刊名称：JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE （ 影响因子：9.4； 五年影响因子：10.6 ）
ISSN： 2190-5991
年卷期： 2024 年
页码：
收录情况： SCI
摘要： The world is facing a global nutrition crisis, as evidenced by the rising incidence of metabolic disorders such as obesity, insulin resistance and chronic inflammation. Skeletal muscle is the largest tissue in humans and plays an important role in movement and host metabolism. Muscle fibre formation occurs mainly during the embryonic stage. Therefore, maternal lifestyle, especially nutrition and exercise during pregnancy, has a critical influence on foetal skeletal muscle development and the subsequent metabolic health of the offspring. In this review, the influence of maternal obesity, malnutrition and micronutrient intake on foetal skeletal muscle development is systematically summarized. We also aim to describe how maternal exercise shapes foetal muscle development and metabolic health in the offspring. The role of maternal gut microbiota and its metabolites on foetal muscle development is further discussed, although this field is still in its 'infancy'. This review will provide new insights to reduce the global crisis of metabolic disorders and highlight current gaps to promote further research.
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