文献类型： 外文期刊
第一作者： Lai, Junhui
作者： Lai, Junhui;Li, Xiuxia;Guan, Weijun;Liang, Ruining;Yang, Qin
作者机构：
关键词： Skeletal Stem Cells; Bovine; Growth Plate; Biological Characterization
期刊名称：JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING （ 影响因子：0.287； 五年影响因子：0.435 ）
ISSN： 2157-9083
年卷期： 2021 年 11 卷 12 期
页码：
收录情况： SCI
摘要： The growth plate is essential in long bone formation and contains a wealth of skeletal stem cells (SSCs). Though the origin and the mechanism for SSCs generation remain uncertain, recent studies demonstrate the transition from cartilage to bone that in the lineage for bone development. SSCs possesses the ability to differentiate into bone and cartilage in vitro. In this research, we aimed to isolate and culture the skeletal stem cells from bovine cattle and then studied its biological characterization. The results showed that these bovine SSCs are positive for PDPN+CD73+CD164+CD90+CD44+ cell surface bio-markers, they are capable of self-renewal and differentiation. Our dates proved that SSCs exists in bovine's long bone.
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