Stilbene Derivatives from Bletilla striata and Their Antiviral Activity

文献类型: 外文期刊

第一作者: Li, Shan-Shan

作者: Li, Shan-Shan;Zheng, Jun-Na;Shen, Si-Yu;Liu, Xiao-Shan;Ma, Yue-Yu;Li, Yin-Ke;Miao, Dong;Wang, Wei-Guang;Hu, Qiu-Fen;Li, Shan-Shan;Shen, Si-Yu;Liu, Xiao-Shan;Gong, Da-Ping;Ma, Xiao-Wei;Li, Yin-Ke;Xiong, Wen

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关键词: Bletilla striata; stilbenes; anti-TMV activities; anti-rotavirus activities

期刊名称:CHEMISTRY OF NATURAL COMPOUNDS ( 影响因子:0.8; 五年影响因子:0.8 )

ISSN: 0009-3130

年卷期: 2023 年

页码:

收录情况: SCI

摘要: Two new (1 and 2), together with five known (3-7) stilbene derivatives, were isolated from the tubers of Bletilla striata. The structures of these new compounds were elucidated by means of spectroscopic methods, while the known compounds were identified by comparison their data with those in the literature. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results revealed that 1 and 2 exhibited potential anti-TMV activities with inhibition rates of 31.5 and 30.6%, respectively, and these rates were close to that of a positive control. Compounds 1 and 2 were also tested for their anti-rotavirus activities, and compounds 1 and 2 showed potential activities with therapeutic index (TI) values of 15.5 and 16.2, respectively. These values are lower than that of a positive control.

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