文献类型： 外文期刊
第一作者： Sun, Lichao
作者： Sun, Lichao;Alper, Hal S.;Alper, Hal S.
作者机构：
关键词： Non-conventional hosts; Fuels; Chemicals; Metabolite building-blocks
期刊名称：CURRENT OPINION IN CHEMICAL BIOLOGY （ 影响因子：8.822； 五年影响因子：8.721 ）
ISSN： 1367-5931
年卷期： 2020 年 59 卷
页码：
收录情况： SCI
摘要： Biotechnology offers a green alternative for the production of fuels and chemicals using microbes. Although traditional model hosts such as Escherichia coli and Saccharomyces cerevisiae have been widely studied and used, they may not be the best hosts for industrial application. In this review, we explore recent advances in the use of nonconventional hosts for the production of a variety of fuel, cosmetics, perfumes, food, and pharmaceuticals. Specifically, we highlight twentyseven popular molecules with a special focus on recent progress and metabolic engineering strategies to enable improved production of fuels and chemicals. These examples demonstrate the promise of nonconventional host engineering.
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