A SET domain-containing protein involved in cell wall integrity signaling and peroxisome biogenesis is essential for appressorium formation and pathogenicity of Colletotrichum gloeosporioides
文献类型： 外文期刊
第一作者： Zhao, Xuanzhu
作者： Zhao, Xuanzhu;Zhang, Junxiang;Xu, Jie;Wang, Na;Zhou, Zongshan;Tang, Bozeng
作者机构：
关键词： Glomerella cingulata; Virulence; Conidiogenesis; Apple; Peroxisome; Anthracnose
期刊名称：FUNGAL GENETICS AND BIOLOGY （ 影响因子：3.495； 五年影响因子：3.831 ）
ISSN： 1087-1845
年卷期： 2020 年 145 卷
页码：
收录情况： SCI
摘要： The chromatin modulator Set5 plays important regulatory roles in both cell growth and stress responses of Saccharomyces cerevisiae. However, its function in filamentous fungi remains poorly understood. Here, we report the pathogenicity-related gene CgSET5 discovered in a T-DNA insertional mutant M285 of Colletotrichum gloeosporioides. Bioinformatic analysis revealed that CgSET5 encodes a SET domain-containing protein that is a homolog of the budding yeast S. cerevisiae Set5. CgSET5 is important for hyphae growth and conidiation and is necessary for appressorium formation and pathogenicity. CgSet5 regulates appressorium formation in a mitogenactivated protein kinase-independent manner. Inactivation of CgSET5 resulted in a significant reduction in chitin content within the cell wall, indicating CgSet5 plays a vital role in cell wall integrity. CgSet5 is involved in peroxisome biogenesis. We identified CgSet5 as the histone H4 methyltransferase, which methylates the critical H4 lysine residues 5 and 8 in C. gloeosporioides. We carried out a yeast two-hybrid screen to find CgSet5 interacting partners. We found CgSet5 putatively interacts with an inorganic pyrophosphatase named CgPpa1, which co-localized in the cytoplasm with CgSet5. Finally, CgPpa1 was found to strongly interact with CgSet5 in vivo during appressorium formation by bimolecular fluorescence complementation assays. These data corroborate a complex control function of CgSet5 acting as a core pathogenic regulator, which connects cell wall integrity and peroxisome biogenesis in C. gloeosporioides.
分类号：
- 相关文献
作者其他论文 更多>>
-
EXPERT expands prime editing efficiency and range of large fragment edits
作者：Xiong, Youcai;Su, Yinyu;He, Ruigao;Han, Xiaosong;Li, Sheng;Liu, Minghuan;Xi, Xiaoning;Liu, Zijia;Wang, Heng;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Ruan, Jinxue;Xiong, Youcai;Su, Yinyu;He, Ruigao;Han, Xiaosong;Li, Sheng;Liu, Minghuan;Xi, Xiaoning;Liu, Zijia;Wang, Heng;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Ruan, Jinxue;Han, Xiaosong;Zhao, Shuhong;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Xie, Shengsong;Xu, Xuewen;Li, Xinyun;Zhao, Shuhong;Li, Kui;Zhang, Jifeng;Xu, Jie
关键词：
-
Novel conjugated 5-alkenyl rhodanine tethered 1,4-benzodioxane derivatives as dual-chitinases inhibitors to hinder the growth of Asian corn borer
作者：Chen, Jinxiu;Shi, Dongmei;Jiang, Zhiyang;Zou, Renxuan;Zhang, Jingyu;Han, Qing;Wang, Na;Duan, Hongxia;Chen, Jinxiu;Shi, Dongmei;Jiang, Zhiyang;Zou, Renxuan;Zhang, Jingyu;Han, Qing;Wang, Na;Duan, Hongxia;Xu, Zhijian;Yang, Qing
关键词：O. furnacalis; Chitinase; 5-alkenylthiazolidinone; 1,4-benzodioxane; Dual-chitinases inhibitor
-
Three New Species and a New Record of Arbuscular Mycorrhizal Fungi of the Genus Acaulospora Associated with Citrus from South China
作者：Huang, Haisi;Qin, Xiaojuan;Xu, Jie;Chen, Tingsu;Zhang, Jinlian;Kang, Yihao;Shang, Pengxiang;Cheng, Tong
关键词：glomeromycota; arbuscular mycorrhizal fungi;
Acaulospora ; phylogenetics; taxonomy -
Role of the cell cycle-related gene cdk2 and its associated ceRNA network in sexual size dimorphism of Cynoglossus semilaevis
作者：Li, Xihong;Wang, Jiacheng;Mai, Jiaqi;Sun, Yuqi;Li, Wenjie;Cai, Zhenyu;Xu, Wenteng;Chen, Zhangfan;Chen, Songlin;Wang, Na;Li, Xihong;Xu, Wenteng;Chen, Zhangfan;Chen, Songlin;Wang, Na;Wang, Jiacheng;Li, Wenjie;Wang, Na
关键词：Cynoglossus semilaevis; Sexual size dimorphism; cdk2; ceRNA
-
Genome-Wide Identification and Characterization of gh/prl/sl Family in Cynoglossus semilaevis
作者：Zhang, Min;Shi, Yuhong;Wang, Zhe;Chen, Zhangfan;Li, Xihong;Xu, Wenteng;Wang, Na;Chen, Zhangfan;Li, Xihong;Xu, Wenteng;Wang, Na
关键词：
gh /prl /sl family; growth hormone receptor; prolactin receptor; Chinese tongue sole (Cynoglossus semilaevis ); pituitary -
Multi-omics analysis of Trichoderma reesei mutant with high glucanase activity
作者：Wang, Na;Lin, Qing;Wang, Zihan;Shi, Honglin;Gao, Yan;Zen, Jun;Lou, Kai;Huo, Xiangdong;Wang, Na;Lin, Qing;Wang, Zihan;Shi, Honglin;Gao, Yan;Zen, Jun;Lou, Kai;Huo, Xiangdong;Wang, Na
关键词：
Trichoderma reesei ; beta-glucanase; Metabolomics; Transcriptomics -
Establishment and characterization of a cell line from Yunlong grouper (Epinephelus moara ♀ and Epinephelus lanceolatus ♂) larva and its response to infectious spleen and kidney necrosis virus infection
作者：Guo, Chenfei;Sha, Zhenxia;Guo, Chenfei;Gong, Zhihong;Fang, Fei;Zhang, Qi;Wang, Na;Su, Yuqin;Wang, Lei;Chen, Songlin;Chen, Songlin
关键词：Yunlong grouper; Larvae; Cell line; Iridovirus; Glar
