Profiling of phenolic acids and flavonoids in sweet potato (Ipomoea batatas L.) leaves and evaluation of their anti-oxidant and hypoglycemic activities

文献类型： 外文期刊

第一作者： Luo, Dan

作者： Luo, Dan;Mu, Taihua;Sun, Hongnan

作者机构：

关键词： Sweet potato leaf; Polyphenols; Flavonoid; Anti-oxidant; Hypoglycemic

期刊名称：FOOD BIOSCIENCE （ 影响因子：4.24； 五年影响因子：4.805 ）

ISSN： 2212-4292

年卷期： 2021 年 39 卷

页码：

收录情况： SCI

摘要： Sweet potato (Ipomoea batatas L.) leaf phenolic acids (SPLPA) and sweet potato leaf flavonoids (SPLF) were characterized using ultra-high-performance liquid chromatography (UHPLC)-hybrid quadrupole-orbitrap mass spectrometry and UHPLC coupled with a diode array detector. The anti-oxidant and hypoglycemic activities were analyzed using 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), 1,1-diphenyl-2-picrylhydrazyl radical scavenging capacity and ferric reducing anti-oxidant powder assays, and alpha-glucosidase and alpha-amylase inhibitory assays. The mechanism of inhibition of SPLPA and SPLF against alpha-glucosidase was studied using kinetic analysis. Thirteen phenolic acids were identified in SPLPA, of which three di-caffeoylquinic acids (60.6%) were most prominent. Ten flavonoids were identified in SPLF and astragalin (28.1%) was the major component. Protocatechualdehyde, ethyl caffeate and quercetin were also identified, showing strong anti-oxidant capacities and inhibition of alpha-glucosidase and alpha-amylase. Kinetic analysis showed that SPLPA and SPLF both reversibly inhibited alpha-glucosidase, in a mixed-type manner, with IC50 values of 330 and 250 mu g/mL, respectively. The results suggested the potential benefits of using sweet potato leaves.

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