The miR172/IDS1 signaling module confers salt tolerance through maintaining ROS homeostasis in cereal crops

文献类型： 外文期刊

第一作者： Cheng, Xiliu

作者： Cheng, Xiliu;He, Qiang;Tang, Sha;Lv, Mingjie;Liu, Huafeng;Gao, Qian;Zhou, Yue;Wang, Qi;Man, Xinyu;Liu, Jun;Wang, Haoran;Liu, Jie;Wang, Haoran;Liu, Jie;Zhang, Xiangxiang;Chen, Tao;Zhang, Xiangxiang;Huang, Rongfeng;Wang, Huan;Chen, Tao;Wang, Huan

作者机构：

关键词： cereal crops; IDS1; miR172; reactive oxygen species (ROS) homeostasis; salt tolerance

期刊名称：NEW PHYTOLOGIST （ 影响因子：10.151； 五年影响因子：10.475 ）

ISSN： 0028-646X

年卷期： 2021 年 230 卷 3 期

页码：

收录情况： SCI

摘要： Salt stress triggers the overdose accumulation of reactive oxygen species (ROS) in crop plants, leading to severe oxidative damage to living tissues. MicroRNAs (miRNAs) act as master regulators orchestrating the stress responsive regulatory networks as well as salt tolerance. However, the fundamental roles of miRNAs in modulating salt tolerance in cereal crops, especially in salt-triggered ROS scavenging remain largely unknown. Through small RNA sequencing, a salt-responsive miRNA, miR172 was identified in rice. Further, by generating the miR172-overexpression or MIR172 gene loss-of-function mutant lines, the biological significance of miR172 and its downstream signaling pathways related to salt tolerance were defined. We demonstrated that miR172 is a positive regulator of salt tolerance in both rice and wheat. More interestingly, miR172a and miR172b, but not miR172c or miR172d are involved in salt stress response, emphasizing the functional differentiation within miR172 family members. Further evidence uncovers a novel miR172/IDS1 regulatory module that functions as a crucial molecular rheostat in maintaining ROS homeostasis during salt stress, mainly through balancing the expression of a group of ROS-scavenging genes. Our findings establish a direct molecular link between miRNAs and detoxification response in cereal crops for improving salt tolerance.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序