Milk biomarkers in relation to inherent and external factors based on metabolomics

文献类型： 外文期刊

第一作者： Zhu, Dan

作者： Zhu, Dan;Chen, Gang;Zhu, Dan;McComb, Kiri;Hayman, Alan;Frew, Russell;Kebede, Biniam

作者机构：

关键词： Milk; Metabolomics; Inherent factor; External factor; Candidate biomarker

期刊名称：TRENDS IN FOOD SCIENCE & TECHNOLOGY （ 影响因子：12.563； 五年影响因子：14.466 ）

ISSN： 0924-2244

年卷期： 2021 年 109 卷

页码：

收录情况： SCI

摘要： Background: Milk is one of the most important food sources for human nutrition. The chemical composition of milk varies depending on many factors and may influence its nutritional value and safety. Metabolomics has recently become one of the major approaches applied to understand the chemical profiles and dynamic changes in milk products. Scope and approach: The increase in the application of metabolomics in milk studies is, in large part, due to the development of high-throughput and high-sensitivity instruments and efficient chemometrics. This review focuses on the changing metabolites in milk, which are relevant to both the inherent factors, such as cow breed, dairy animal species and lactation stage, and external factors, including diet, season, geographic origin, disease, processing and storage stability. Additionally, the applications of candidate biomarkers for milk authentication are reviewed. Key findings and conclusions: The candidate biomarkers identified in previous studies are listed in this review. Also, some metabolites, which could be used as robust biomarkers, such as choline, citrate, valine, hippuric acid, 2-butanone, lactate and some fatty acids, for milk quality, traceability and safety studies are summarized. Challenges for this scientific field are also addressed.

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