Isolation and pathogenicity analysis of mink orthoreoviruses

文献类型： 外文期刊

第一作者： Ren, Jingqiang

作者： Ren, Jingqiang;Ren, Jingqiang;Sun, Na;Zhang, Ping;Guo, Li;Cheng, Shipeng;Ren, Jingqiang;Liu, Wei;Yin, Mei;Zhang, Hewei

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关键词： mammalian orthoreoviruses; mink; pathogenicity

期刊名称：TRANSBOUNDARY AND EMERGING DISEASES （ 影响因子：5.005； 五年影响因子：4.622 ）

ISSN： 1865-1674

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收录情况： SCI

摘要： Mammalian orthoreoviruses (MRVs) can infect many mammals including human, and numerous higher virulent MRVs have been reported in recent years. The first mink orthoreovirus was reported in China in 2011. In the present study, three new strains of mammalian orthoreoviruses were isolated from mink and found to be most closely related to human strain MRV2Tou05 and other human strains. Mink experiments demonstrated that the isolated mink reoviruses did not lead to severe pathogenicity. Viruses were eliminated within 2 weeks after infection, but they may cause viral enteritis disease in puppies.

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