文献类型： 外文期刊
第一作者： Ge, Shikun
作者： Ge, Shikun;Liu, Xiang;Zhang, Xiaoying;Ge, Shikun;Zhang, Xiaoying;Zhang, Xiaoying;Zhang, Xingxing;Zhong, Fagang;Zhang, Xiaoying
作者机构：
关键词： Antibody mimetics; IgY-peptide; Canine parvovirus (CPV); IgY-scFv; IgY technology
期刊名称：VETERINARY RESEARCH （ 影响因子：3.357； 五年影响因子：3.432 ）
ISSN： 0928-4249
年卷期： 2021 年 52 卷 1 期
页码：
收录情况： SCI
摘要： Antibody mimetics may be used for various biomedical applications, especially those for which conventional antibodies are ineffective. In this study, we developed a smaller molecular chicken IgY mimetic peptide (IgY-peptide) based on the complementarity-determining regions (CDRs) of the anti-canine parvovirus (CPV) IgY-scFv prepared previously. The mimetic peptide showed no cross-reactivity with canine distemper virus (CDV) and canine coronavirus (CCV) and showed excellent protective properties for Crandell-Rees Feline Kidney (CRFK) cells against CPV. This study is the first attempt to develop a mimetic IgY-peptide and demonstrates the ease and feasibility in generating such a novel antibody-like functional molecule for biomedical purposes.
分类号：
- 相关文献
作者其他论文 更多>>
-
Simulation of the nutritional requirements and energy balance of adult cows in a northern temperate grassland
作者：Yu, Tianqi;Yan, Ruirui;Xin, Xiaoping;Zhang, Xiaoying;Yin, Guomei
关键词：pasture management; energy balance; Hulunbuir grassland; forage-livestock balance; livestock management
-
Geography, phylogeny and host switch drive the coevolution of parasitic Gyrodactylus flatworms and their hosts
作者：Lei, Hong-Peng;Jakovlic, Ivan;Liu, Xiang;Yan, Chuan;Zhang, Dong;Lei, Hong-Peng;Jakovlic, Ivan;Liu, Xiang;Yan, Chuan;Zhang, Dong;Zhou, Shun;Jin, Xiao;Wang, Bo;Li, Wen-Xiang;Wang, Gui-Tang;Li, Wen-Xiang;Wang, Gui-Tang
关键词：Host-parasite interactions; Host specificity; Host use; Co-phylogeny; Coevolutionary events; Bipartite network
-
Influenza virus detection using an electrochemical biosensor based on DSN and RCA
作者：Yang, Yuqi;Bu, Shengjun;He, Xiuxia;Yang, Yuqi;Bu, Shengjun;Zhang, Xiaoying;Duan, Qiqing;Meng, Heyuan;Hao, Zhuo;Wan, Jiayu
关键词：nuclease (DSN) rolling circle amplification; (RCA)
-
Effects of the Glycosylation of the HA Protein of H9N2 Subtype Avian Influenza Virus on the Pathogenicity in Mice and Antigenicity
作者：Liang, Bing;Fan, Menglu;Meng, Qi;Jin, Jiayu;Chen, Na;Lu, Yuanlu;Jiang, Chenfeng;Zhang, Xingxing;Zou, Zongyou;Ping, Jihui;Su, Juan;Liang, Bing;Fan, Menglu;Meng, Qi;Jin, Jiayu;Chen, Na;Lu, Yuanlu;Jiang, Chenfeng;Zhang, Xingxing;Zou, Zongyou;Ping, Jihui;Su, Juan;Zhang, Yaping
关键词：
-
STnc1280, a trans- coding sRNA is involved in virulence modulation via targeting gldA mRNA in Salmonella Typhimurium
作者：Ning, Chengcheng;Li, Na;Wang, Lixia;Guo, Yun;Ji, Chunhui;Li, Zhiyuan;Shang, Yunxia;Sun, Yaoqiang;Huang, Xiaoxing;Leng, Qingwen;Meng, Qingling;Qiao, Jun;Ning, Chengcheng;Zhang, Xingxing;Cai, Xuepeng
关键词：modulation; Salmonella Typhimurium; sRNA; STnc1280; virulence
-
Single-cell transcriptome landscape of zebrafish liver reveals hepatocytes and immune cell interactions in understanding nonalcoholic fatty liver disease
作者：Huang, Yingyi;Liu, Xiang;Wang, Hong-Yan;Li, Yubang;Liu, Kaiqiang;Wang, Qian;Shao, Changwei;Huang, Yingyi;Liu, Xiang;Wang, Hong-Yan;Li, Yubang;Liu, Kaiqiang;Wang, Qian;Shao, Changwei;Chen, Jian-Yang;Zhang, Xianghui;Lu, Yifang;Wang, Qian;Fan, Guangyi;Chen, Jian-Yang;Zhang, Xianghui;Lu, Yifang;Fan, Guangyi;Dong, Zhongdian;Wang, Zhongduo;Liu, Shanshan;Fan, Guangyi;Liu, Shanshan;Zou, Jun
关键词：
-
Enhancing Pseudomonas syringae pv. Actinidiae sensitivity in kiwifruit by repressing the NBS-LRR genes through miRNA-215-3p and miRNA-29-3p identification
作者：Jiang, Chengyao;Rao, Jiahui;Lu, Wei;Li, Mengyao;Zheng, Yangxia;Zhang, Xiaoying;Luo, Shu;Luo, Liang;Ren, Dan;Liu, Jiaming;Zhao, Shumei;Song, Yu;Sun, Yin-Biao
关键词：Kiwifruit bacterial canker; PSA; DEMs and DEGs; miRNA-215-3p and miRNA-29-3p; NBS-LRR
