Diurnal expression of CXC receptors 4 (CXCR4) and CXC chemokine ligand 12 (CXCL12) in Pelteobagrus vachellii
文献类型： 外文期刊
第一作者： Qin, Chuanjie
作者： Qin, Chuanjie;Memon, Nazakat Hussain;Shi, Qinchao;Qin, Chuanjie;Memon, Nazakat Hussain;Shi, Qinchao;Gong, Quan;Yang, Qingfa
作者机构：
关键词： CXC receptors 4; CXC chemokine ligand 12; diurnal expression; innate immune; pelteobagrus vachellii
期刊名称：CHRONOBIOLOGY INTERNATIONAL （ 影响因子：2.486； 五年影响因子：2.913 ）
ISSN： 0742-0528
年卷期：
页码：
收录情况： SCI
摘要： The CXC chemokine ligand 12/CXC receptor 4 ligand/receptor interaction is the most ancient chemokine system in vertebrates, and it plays a pivotal role in the immune system's response against bacterial infection. In the current study, 1211 bp CXCR4 and 937 bp CXCL12 genes, which encode 364 and 99 amino acids, respectively, were isolated. Within the 24-hour light/dark cycle, the maximum of CXCR4 in the intestine, spleen, and anterior kidney of Pelteobagrus vachellii occurs at 8:00, 16:00, and 16:00, respectively. The maximum of CXCL12 in the intestine, spleen, and anterior kidney of P. vachellii occurs at 20:00, 12:00, and 20:00, respectively. CXCR4 and CXCL12 expressions showed 24-hour variation, which contributed to understanding of the immune rhythm of the teleost.
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