Effect of Food Endotoxin on Infant Health

文献类型： 外文期刊

第一作者： Wu, Haoming

作者： Wu, Haoming;Li, Huiying;Meng, Lu;Zheng, Nan;Wang, Jiaqi;Wu, Haoming;Li, Huiying;Meng, Lu;Zheng, Nan;Wang, Jiaqi;Wu, Haoming;Li, Huiying;Meng, Lu;Zheng, Nan;Wang, Jiaqi;Wang, Yang

作者机构：

关键词： endotoxin; infant formula; infant health; alkaline phosphatase

期刊名称：TOXINS （ 影响因子：3.531； 五年影响因子：3.832 ）

ISSN：

年卷期： 2021 年 13 卷 5 期

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收录情况： SCI

摘要： Endotoxin is a complex molecule derived from the outer membrane of Gram-negative bacteria, and it has strong thermal stability. The processing of infant food can kill pathogenic bacteria but cannot remove endotoxin. Because the intestinal structure of infants is not fully developed, residual endotoxin poses a threat to their health by damaging the intestinal flora and inducing intestinal inflammation, obesity, and sepsis, among others. This paper discusses the sources and contents of endotoxin in infant food and methods for preventing endotoxin from harming infants. However, there is no clear evidence that endotoxin levels in infant food cause significant immune symptoms or even diseases in infants. However, in order to improve the safety level of infant food and reduce the endotoxin content, this issue should not be ignored. The purpose of this review is to provide a theoretical basis for manufacturers and consumers to understand the possible harm of endotoxin content in infant formula milk powder and to explore how to reduce its level in infant formula milk powder. Generally, producers should focus on cleaning the milk source, securing the cold chain, avoiding long-distance transportation, and shortening the storage time of raw milk to reduce the level of bacteria and endotoxin. After production and processing, the endotoxin content should be measured as an important index to test the quality of infant formula milk powder so as to provide high-quality infant products for the healthy growth of newborns.

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