Genomic Sequence Analysis of Bombyx mori Nucleopolyhedrovirus Isolated from Yunnan Sericulture Region, China

文献类型： 外文期刊

第一作者： Zhang, Yonghong

作者： Zhang, Yonghong;Shao, Yulan;Su, Zhenguo;Ni, Jing;Bai, Xingrong;Zhu, Feng

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关键词： Bombyx mori; Complete genome; Baculovirus; BmNPV isolate; Baoshan isolate

期刊名称：INDIAN JOURNAL OF MICROBIOLOGY （ 影响因子：1.83； 五年影响因子：1.87 ）

ISSN： 0046-8991

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收录情况： SCI

摘要： The blood pathogens of grasserie caused by Bombyx mori nucleopolyhedrovirus BmNPV have a serious impact on the sericulture industry. To understand the genetic status of BmNPV endemic strains in the Yunnan sericulture region, the structure and complete genome sequence of BmNPV isolated from Baoshan city of Yunnan Province were described and compared to known strains. The BmNPV-Baoshan isolate was a nucleopolyhedrovirus parasitized in silkworm larvae. Its genome has 128, 452 bp with a G + C content of 40.4%. Phylogenetic analysis clustered the virus with China BmNPV isolates; BmNPV-Baoshan was closely related to BomaNPV-S1 (both strains originated from the same ancestor). BmNPV-Baoshan strain has bro-b gene deletion, hr1 missing 4 repeat units of 30-bp palindrome structure compared to BmNPV-T3 strain. The aim of this study was to elucidate the evolution of the virus further and provide insights for the protection of virus-induced hematologic sepsis.

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