Applications of CRISPR technology in studying plant-pathogen interactions: overview and perspective

文献类型： 外文期刊

第一作者： Gosavi, Gokul

作者： Gosavi, Gokul;Yan, Fang;Ren, Bin;Kuang, Yongjie;Yan, Daqi;Zhou, Xueping;Zhou, Huanbin;Ren, Bin;Zhou, Huanbin;Zhou, Xueping

作者机构：

关键词： Genome editing; CRISPR; Plant-pathogen interaction; Crop improving

期刊名称：PHYTOPATHOLOGY RESEARCH （ 影响因子：3.955； 五年影响因子：3.955 ）

ISSN： 2096-5362

年卷期： 2020 年 2 卷 1 期

页码：

收录情况： SCI

摘要： Targeted genome editing technology is becoming one of the most important genetic tools and widely employed in the plant pathology community. In recent years, CRISPR (Clustered regularly interspaced short palindromic repeats) and CRISPR-associated proteins discovered in the adaptive immune system in prokaryotes have been successfully reprogrammed into various genome editing tools and have caught the attention of the scientific community due to its simplicity, high efficiency, versatility. Here, we provide an overview of various CRISPR/Cas systems, the derived tools and their applications in plant pathology. This review highlights the advantages of knocking-out techniques to target major susceptibility genes and negative regulators of host defense pathways for gaining resistance to bacterial, fungal and viral pathogens in model and crop plants through utilizing the CRISPR/Cas-based tools. Besides, we discuss the possible strategies of employing the CRISPR-based tools for both fundamental studies on plant-pathogen interactions and molecular crop breeding towards the improvement of resistance in the future.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序