文献类型： 外文期刊
第一作者： Mao, Qian-Qian
作者： Mao, Qian-Qian;Xu, Xiao-Yu;Shang, Ao;Li, Hua-Bin;Gan, Ren-You;Gan, Ren-You;Wu, Ding-Tao;Atanasov, Atanas G.;Atanasov, Atanas G.;Atanasov, Atanas G.;Atanasov, Atanas G.
作者机构：
关键词： phytochemicals; gastric cancer; anticancer; mechanism of action
期刊名称：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES （ 影响因子：5.923； 五年影响因子：6.132 ）
ISSN：
年卷期： 2020 年 21 卷 2 期
页码：
收录情况： SCI
摘要： Gastric cancer is the fifth most common cancer, and the third most prevalent cause of cancer-related deaths in the world. Voluminous evidence has demonstrated that phytochemicals play a critical role in the prevention and management of gastric cancer. Most epidemiological investigations indicate that the increased intake of phytochemicals could reduce the risk of gastric cancer. Experimental studies have elucidated the mechanisms of action, including inhibiting cancer cell proliferation, inducing apoptosis and autophagy, and suppressing angiogenesis as well as cancer cell metastasis. These mechanisms have also been related to the inhibition of Helicobacter pylori and the modulation of gut microbiota. In addition, the intake of phytochemicals could enhance the efficacy of anticancer chemotherapeutics. Moreover, clinical studies have illustrated that phytochemicals have the potential for the prevention and the management of gastric cancer in humans. To provide an updated understanding of relationships between phytochemicals and gastric cancer, this review summarizes the effects of phytochemicals on gastric cancer, highlighting the underlying mechanisms. This review could be helpful for guiding the public in preventing gastric cancer through phytochemicals, as well as in developing functional food and drugs for the prevention and treatment of gastric cancer.
分类号：
- 相关文献
作者其他论文 更多>>
-
Untargeted metabolomics analysis of non-volatile metabolites and dynamic changes of antioxidant capacity in Douchi with edible mushroom by-products
作者：Rong, Pei-Xiu;Wu, Ding-Tao;Geng, Fang;Rong, Pei-Xiu;He, Xiao-Qin;Liu, Yi;Liu, Hong-Yan;Ayyash, Mutamed;Li, Hua-Bin;Ng, Siew Bee;Gan, Ren-You
关键词：Singapore; Douchi; Fermentation; UPLC-MS/MS; Metabolomics; Antioxidant activity
-
Comparison of soluble dietary fibers from various quinoa microgreens: Structural characteristics and bioactive properties
作者：Wu, Ding -Tao;Li, Jie;Wang, Jin;Lei, Jing;Hu, Yi-Chen;Wu, Xiao-Yong;Zou, Liang;Wu, Ding -Tao;Li, Jie;Wang, Jin;Lei, Jing;Gan, Ren-You;Qin, Peiyou
关键词：Quinoa microgreen; Soluble dietary fiber; Pectic -polysaccharide; Molecular weights; Constituent monosaccharide; Antioxidant effect; Antiglycation effect; Prebiotic effect; Immunoregulatory effect
-
Discovery of Curcuminoids as Pancreatic Lipase Inhibitors from Medicine-and-Food Homology Plants
作者：He, Xiao-Qin;Zou, Hai-Dan;Liu, Yi;Xia, Yu;Liu, Hong-Yan;He, Xiao-Qin;Chen, Xue-Jiao;Wang, Xiao-Li;Atanasov, Atanas G.;Atanasov, Atanas G.;Matin, Maima;Ng, Siew Bee;Gan, Ren-You;Wu, Ding-Tao;Gan, Ren-You
关键词：medicine-and-food homology plants; pancreatic lipase; enzyme inhibition; affinity ultrafiltration; docking simulations
-
Efficient extraction of pectic polysaccharides from thinned unripe kiwifruits by deep eutectic solvent-based methods: Chemical structures and bioactivities
作者：Wu, Ding -Tao;Geng, Jin-Lei;Li, Jie;Deng, Wen;Hu, Yi-Chen;Zou, Liang;Geng, Jin-Lei;Deng, Wen;Xia, Yu;Liu, Hong-Yan;Zhang, Yao;Zhuang, Qi-Guo;Gan, Ren-You
关键词：Thinned young kiwifruit; Deep eutectic solvent; Pectic polysaccharide; Structural feature; Biological function
-
Recent advances in the influences of drying technologies on physicochemical properties and biological activities of plant polysaccharides
作者：Guo, Huan;Gao, Hong;Guo, Huan;Gao, Hong;Guo, Huan;Liu, Hong-Yan;Li, Hang;Wu, Ding-Tao;Zhong, Linda L. D.;Gan, Ren-You
关键词：Biological properties; drying; molecular mechanisms; plant polysaccharides; structural properties
-
Theabrownin inhibits obesity and non-alcoholic fatty liver disease in mice via serotonin-related signaling pathways and gut-liver axis
作者：Li, Hang -Yu;Huang, Si -Yu;Zhou, Dan -Dan;Xiong, Ruo-Gu;Luo, Min;Saimaiti, Adila;Zhu, Hui-Lian;Li, Hua-Bin;Han, Mu-Ke;Gan, Ren-You
关键词：Non-alcoholic fatty liver disease; Anti-obesity; Theabrownin; Serotonin; Gut microbiota
-
Dietary factors in nonalcoholic fatty liver disease: impacts on human and animal health - a review
作者：Yeung, Andy Wai Kan;Yeung, Andy Wai Kan;Litvinova, Olena;Atanasov, Atanas G.;Ksepka, Natalia;Matin, Maima;Horbanczuk, Jaroslaw Olav;Wysocki, Kamil;Mickael, Michel-Edwar;Lawinski, Michal;Atanasov, Atanas G.;Wang, Dongdong;Souto, Eliana B.;Souto, Eliana B.;Stoyanov, Jivko;Stoyanov, Jivko;Echeverria, Javier;Tewari, Devesh;Lucarini, Massimo;Durazzo, Alessandra;Pirgozliev, Vasil;Gan, Ren-You;Gan, Ren-You;Tzvetkov, Nikolay T.;Matin, Farhan Bin;Litvinova, Olena;Bishayee, Anupam;Devkota, Hari Prasad;El-Demerdash, Amr;El-Demerdash, Amr;Brncic, Mladen;Santini, Antonello;Horbanczuk, Olaf. K.;Das, Niranjan;Siddiquea, Bodrun Naher;Hrg, Dalibor;Hrg, Dalibor
关键词：NAFLD; obesity; liver; resveratrol; curcumin; bibliometrics; Web of Science; VOSviewer
