Chemical Constituents from Nicotiana tabacum L. and Their Antifungal Activity

文献类型: 外文期刊

第一作者: Yang, Chen

作者: Yang, Chen;Liu, Su;Li, Mao-Ye;Xie, Sheng-Nan;Du, Yong-Mei;Xu, Kuo;Ni, Lin;Xu, Kuo

作者机构:

关键词: Nicotiana tabacum; Valsa mali var; mali; Alternaria porri; Botrytis cinerea; antifungal activity

期刊名称:NATURAL PRODUCT COMMUNICATIONS ( 影响因子:0.986; 五年影响因子:1.068 )

ISSN: 1934-578X

年卷期: 2021 年 16 卷 11 期

页码:

收录情况: SCI

摘要: A phytochemical investigation of an aqueous ethyl alcohol (EtOH) extract of the flowers of Nicotiana tabacum L. led to the identification of one new eudesmane-type sesquiterpenoid (1) and 14 known compounds, including 7 flavones (2-8), 6 phenolic acids (9-14), and 1 coumarin (15). The chemical structure of 1 was established on the basis of high-resolution electrospray ionization (HRESIMS) and 1D and 2D NMR analyses, while the other structures were elucidated by 1D NMR and LC-MS data. The antiphytopathogenic activities of all the isolated compounds were tested to determine their antifungal activity against Valsa mali var. mali, Alternaria porri, and Botrytis cinerea at a concentration of 10 mu g/mL. Compound 4 exhibited more potent antifungal effects against Valsa mali var. mali with a % growth inhibition of 47.9 +/- 1.2%, while the others only showed insignificant activities.

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[1]Sesquiterpenoids and Diterpenoids from the Flowers of Nicotiana tabacum L. and Their Antifungal Activity. Xu, Kuo,Wang, Jiao,Liu, Jing,Du, Yongmei,Xu, Kuo,Wei, Xiaoyi,Ni, Lin. 2022

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