Phenolic Glucosides from the Leaves of Vitex negundo var. cannabifolia

文献类型: 外文期刊

第一作者: Sun, Jing

作者: Sun, Jing;Li, Manman;Chang, Chuang;Pei, Yujie;Zhao, Yunfang;Zheng, Jiao;Song, Yuelin;Tu, Pengfei;Huo, Huixia;Li, Jun;Sun, Jing;Wang, Yongru;Zeng, Kewu

作者机构:

关键词: Verbenaceae; Vitex negundo var; cannabifolia; phenolic glucosides; anti-inflammation

期刊名称:CHEMISTRY & BIODIVERSITY ( 影响因子:2.745; 五年影响因子:2.581 )

ISSN: 1612-1872

年卷期: 2022 年 19 卷 11 期

页码:

收录情况: SCI

摘要: Four new phenolic glucosides, cannabifolins G-J (1-4), together with four known ones (5-8), were isolated from the leaves of Vitex negundo var. cannabifolia. Their structures were established by comprehensive analysis of 1D and 2D NMR data and comparison of their spectroscopic and physical data with the literature values. Compound 7 exhibited weak inhibition of nitric oxide production stimulated by lipopolysaccharide in BV-2 microglial cells with IC50 value of 132.8 mu M.

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