Differential Analysis of Pomelo Peel Fermentation by Cordyceps militaris Based on Untargeted Metabolomics

文献类型： 外文期刊

第一作者： Xiang, Yannan

作者： Xiang, Yannan;Tian, Siyi;Luo, Xinyu;Cai, Chenggang;Du, Yaowen;Yang, Hailong;Gao, Haiyan

作者机构：

关键词： pomelo peel; Cordyceps militaris; fermentation; multivariate statistical analysis; untargeted metabolomics

期刊名称：PROCESSES （ 影响因子：3.5； 五年影响因子：3.4 ）

ISSN：

年卷期： 2024 年 12 卷 4 期

页码：

收录情况： SCI

摘要： The content of differentially abundant metabolites in the fermentation broth of grapefruit peels fermented by Cordyceps militaris at different fermentation times was analyzed via LC-MS/MS. Small molecule metabolites and differential metabolic pathways were analyzed via multivariate analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment. A total of 423 metabolites were identified at 0, 2, 6, and 10 days after fermentation. Among them, 169 metabolites showed differential abundance, with significant differences observed between the fermentation liquids of every two experimental groups, and the metabolite composition in the fermentation liquid changed over the fermentation time. In summary, the upregulation and downregulation of metabolites in cancer metabolic pathways collectively promote the remodeling of cancer cell metabolism, facilitating increased glycolysis, alterations in TCA cycle flux, and enhanced biosynthesis of the macromolecules required for rapid proliferation and survival. This study provides new perspectives on the development of high-value-added agricultural and forestry byproducts and the development and research of functional foods.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序