Characterization of novel loci controlling seed oil content in Brassica napus by marker metabolite-based multi-omics analysis
文献类型： 外文期刊
第一作者： Li, Long
作者： Li, Long;Tian, Zhitao;Chen, Jie;Tan, Zengdong;Zhang, Yuting;Zhao, Hu;Wu, Xiaowei;Yao, Xuan;Chen, Wei;Guo, Liang;Li, Long;Tian, Zhitao;Chen, Jie;Tan, Zengdong;Zhang, Yuting;Zhao, Hu;Wu, Xiaowei;Yao, Xuan;Chen, Wei;Guo, Liang;Wen, Weiwei;Wen, Weiwei;Chen, Wei;Guo, Liang;Wen, Weiwei;Chen, Wei;Guo, Liang
作者机构：
关键词： Brassica napus; Metabolomics; mGWAS; mTWAS; WGCNA; Seed oil content
期刊名称：GENOME BIOLOGY （ 影响因子：12.3； 五年影响因子：17.4 ）
ISSN： 1474-760X
年卷期： 2023 年 24 卷 1 期
页码：
收录情况： SCI
摘要： BackgroundSeed oil content is an important agronomic trait of Brassica napus (B. napus), and metabolites are considered as the bridge between genotype and phenotype for physical traits.ResultsUsing a widely targeted metabolomics analysis in a natural population of 388 B. napus inbred lines, we quantify 2172 metabolites in mature seeds by liquid chromatography mass spectrometry, in which 131 marker metabolites are identified to be correlated with seed oil content. These metabolites are then selected for further metabolite genome-wide association study and metabolite transcriptome-wide association study. Combined with weighted correlation network analysis, we construct a triple relationship network, which includes 21,000 edges and 4384 nodes among metabolites, metabolite quantitative trait loci, genes, and co-expression modules. We validate the function of BnaA03.TT4, BnaC02.TT4, and BnaC05.UK, three candidate genes predicted by multi-omics analysis, which show significant impacts on seed oil content through regulating flavonoid metabolism in B. napus.ConclusionsThis study demonstrates the advantage of utilizing marker metabolites integrated with multi-omics analysis to dissect the genetic basis of agronomic traits in crops.
分类号：
- 相关文献
作者其他论文 更多>>
-
Effect of crowding stress on liver health, gut permeability and gut microbiota of genetically improved farmed tilapia (GIFT, Oreochromis niloticus)
作者：Zhang, Jian;Chen, Jie;Liang, Hui;Li, Ming;Zhou, Wenhao;Zhou, Zhigang;Yang, Yalin;Zhang, Zhen;Ran, Chao;Ding, Qianwen
关键词：Crowing stress; Apoptosis; Gut permeability; Gut microbiota; GIFT
-
Telomere-to-telomere genome assembly of eggplant ( Solanum melongena L.) promotes gene fine localization of the green stripe (GS) in pericarp
作者：Fang, Huarong;Wu, Jie;Xie, Liang;Li, Yizhiqi;Huang, Jingjing;Yan, Xiaoyun;He, Xuehan;Deng, Wentao;Li, Ruirui;Yu, Wenjin;Wang, Peng;Chen, Jie;Ji, Yanhai;Wen, Changlong
关键词：Eggplant; T2T genome; Green stripe
-
A portable LED-induced fluorescence system for quantitative detection of different kinds of vegetable oil adulteration
作者：Liu, QingHua;Zhang, Yifan;Wu, Meifeng;Li, Minmin;Tong, Litao;Yang, Huihui;Fan, Bei;Wang, Fengzhong;Li, Long;Zhang, Yifan;Wang, Fengzhong;Li, Long;Zhang, Yifan;Yang, Huihui;Li, Long;Liu, Jun
关键词：Vegetable oils; Adulteration; Portable system; Normalized spectral ratio (NSR); Quantitative
-
GLR36T807I Mutation of Casuarina equisetifoli Is Associated With a Decreased JA Response to Insect Feeding by Lymantria xylina
作者：Chang, Huan;Su, Jun;Li, Chengli;Zhu, Tengfei;Cai, Shouping;Chen, Jie;Zhan, Fangfang;Zeng, Liqiong;Ye, Gongfu;Fang, Yu;Li, Jian
关键词：
Casuarina equisetifolia ; flavonoids; glutamate receptor-like protein 3.6 (GLR3.6); jasmonic acid;Lymantria xylina ; phosphorylation -
A strategy to improve the detection accuracy and universality of highland barley muti-quality attributes based on near infrared spectroscopy combined with model transfer method
作者：Li, Linglei;Li, Long;Li, Jingfeng;Yang, Jingjing;Jia, Lang;Fan, Bei;Tong, Litao;Liu, Liya;Huang, Yatao;Wang, Fengzhong;Wang, Lili;Li, Long;Wang, Fengzhong;Fan, Bei;Huang, Yatao;Wang, Fengzhong;Yang, Xiaolong
关键词：Highland barley; Near-infrared spectroscopy; Direct standardization; Piecewise direct standardization; Model transfer; Scatter correction; Powder
-
Study on optimization of extraction and purification processes for total flavonoids from Lycopi herba roots and their anti-proliferative effects on fibrous synoviocytes in human rheumatoid arthritis
作者：Chen, Jie;Jiang, Chunyang;Liu, Zhenyu;Wang, Panpan;Zhou, Nong;Chen, Jie;Ma, Qiang;Jiang, Chunyang
关键词：Lycopi herba root; Total flavonoids; Ultrasonic; Response surface methodology; Cell proliferation
-
A wheat phytohormone atlas spanning major tissues across the entire life cycle provides novel insights into cytokinin and jasmonic acid interplay
作者：Yin, Huanran;Liu, Wei;Hu, Xin;Jia, Jingqi;Liu, Mengmeng;Wei, Jiaqi;Cheng, Yikeng;Gong, Xin;Li, Qiang;Yan, Wenhao;Chen, Wei;Jia, Jizeng;Gao, Lifeng;Fernie, Alisdair R.
关键词：wheat; phytohormones; metabolic regulatory network; DOF
